Evidence map›Paper›PMID 30996040›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2019

Endobronchial valves for severe emphysema.

Jorine E Hartman, Lowie E G W Vanfleteren, Eva M van Rikxoort, Karin Klooster, Dirk-Jan Slebos

2 registry-linked trialsOpen access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04801108 narecruitingnot on this mapstarted 2021, after this paper: background citation

Combined Zephyr Valve System With Inter-lobar Fissure Completion for Lung Volume Reduction in Emphysema: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2021 to 2026Enrolled20ConditionsEmphysema or COPDArmsRobotic or VATS lobar fissure completion, Endobronchial valves placement
NCT05257681 narecruitingnot on this mapstarted 2022, after this paper: background citation

Inter-lobar Fissure Completion as a Salvage Treatment in Patients With Failed Bronchoscopic Lung Volume Reduction

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2022 to 2027Enrolled20ConditionsEmphysema or COPDArmsInterlobar fissure completion and pleural adhesiolysis
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Guideline
  2. Observational
  3. Review
  4. Bronchoscopic endobronchial valves.Breathe (Sheffield, England) · 2026
    Review
  5. Endobronchial Valve Treatment Improves Regional Specific Ventilation in the Target Lung.Respiration; international review of thoracic diseases · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Anesthesia for Bronchoscopy-An Update.Journal of clinical medicine · 2024
    Review
  16. Lung volume reduction: surgeryBreathe (Sheffield, England) · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jorine E HartmanDept of Pulmonary diseases, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands j.hartman@umcg.nl.
Lowie E G W VanfleterenCOPD Centre, Sahlgrenska University Hospital and Institute of Medicine, Gothenburg University, Gothenburg, Sweden.ORCID https://orcid.org/0000-0002-4387-4096
Eva M van RikxoortDepat of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
Karin KloosterDept of Pulmonary diseases, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Dirk-Jan SlebosDept of Pulmonary diseases, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
University Medical Center Groningen · NLMaastricht University Medical Centre · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The results of the randomised controlled trials investigating the bronchoscopic lung volume reduction treatment using endobronchial valves (EBV) are promising, and have led to their inclusion in treatment guidelines, US Food and Drug Administration approval and inclusion in routine care in an increasing number of countries. The one-way valve treatment has advanced and is now a regular treatment option. However, this new phase will lead to new challenges in terms of implementation. We believe that key issues in future research concern advanced patient selection, improved methods for target lobe selection, increased knowledge on the predictive risk of a pneumothorax, positioning of pulmonary rehabilitation in conjunction with the EBV treatment, the positioning of lung volume reduction surgery

Indexed as

BronchoscopyHumansLungProsthesis DesignProsthesis ImplantationPulmonary EmphysemaRandomized Controlled Trials as TopicRecovery of FunctionTreatment Outcome

Identifiers

PMID30996040
PMCPMC9488629
OpenAlexW2939874264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.