Evidence map›Paper›PMID 30995952›Full record

Trial reportDeutsches Arzteblatt international2019

Panic Disorder in Primary Care.

Jochen Gensichen, Thomas S Hiller, Jörg Breitbart, Christian Brettschneider, Tobias Teismann, Ulrike Schumacher, Karoline Lukaschek, Mercedes Schelle, Nico Schneider, Michael Sommer and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Jochen GensichenInstitute of General Practice and Family Medicine, University Hospital of the Ludwig-Maximilians University of Munich, Munich, Germany
Thomas S HillerInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Jörg BreitbartInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Christian BrettschneiderInstitute of Health Economics and Health Care Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Tobias TeismannMental Health Research and Treatment Center, Ruhr-University Bochum, Bochum, Germany
Ulrike SchumacherCenter for Clinical Studies, Jena University Hospital, Jena, Germany
Karoline LukaschekInstitute of General Practice and Family Medicine, University Hospital of the Ludwig-Maximilians University of Munich, Munich, Germany
Mercedes SchelleInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Nico SchneiderInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Michael SommerInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Michel WensingInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany
Hans-Helmut KönigInstitute of Health Economics and Health Care Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Jürgen MargrafMental Health Research and Treatment Center, Ruhr-University Bochum, Bochum, Germany
Jena-PARADISE Study Group
LMU Klinikum · DEJena University Hospital · DERuhr University Bochum · DEHeidelberg University · DELudwig-Maximilians-Universität München · DEUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated a team-based program of exercises for patients with panic disorder with or without agoraphobia (PDA) in primary care.

methods419 patients with PDA (mean age 46.2 years, standard deviation 14.4 years; 74% female) were included in this cluster-randomized, controlled intervention trial. The patients were blinded with respect to their group assignment at baseline. Patients in the intervention group (36 primary-care practices, 230 patients) underwent a 23-week exercise program combined with case management, while patients in the control group (37 practices, 189 patients) received standard care. Symptoms of anxiety (according to the Beck Anxiety Inventory, BAI) at six months were the primary endpoint. Patients were followed up at six months (n = 338, 81%) and at twelve months (n = 318, 76%). The analysis was by intention to treat.

resultsSymptoms of anxiety improved to a significantly greater extent in the intervention group (p = 0.008). The intergroup dif- ference in the reduction of the BAI score (range: 0-63) was 3.0 points (95% confidence interval [-5.8; -0.2]) at six months and 4.0 points [-6.9; -1.2] at twelve months. In the intervention group, there was a significantly greater reduction in the frequency of panic attacks (p = 0.019), in avoidant behavior (p = 0.016), and in depressiveness (p<0.001), as well as a greater improvement of the quality of treatment (p<0.001).

conclusionIn primary-care patients who have panic disorder with or without agoraphobia, a team-based exercise program combined with case management can improve symptoms to a greater extent than standard primary-care treatment.

Indexed as

Primary Health CareAgoraphobiaCase ManagementExercise TherapyFemaleHumansMaleMiddle AgedPanic DisorderPsychotherapy, GroupTreatment Outcome

Identifiers

PMID30995952
PMCPMC6482367
OpenAlexW2989416841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.