ArticleBMC evolutionary biology2019
Variation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus.
Article in BMC evolutionary biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026Review
- Consuming your colors: carotenoid and retinol availability affects expression of color related genes in the mimic poison frog (Ranitomeya imitator).BMC genomics · 2025Article
- Long-term evolutionary persistence of a cryptic color polymorphism in frogs.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Expression patterns of melanin-related genes are linked to crypsis and conspicuousness in a pumpkin toadlet.Molecular ecology · 2025Article
- Comparison of Transcriptome Differences in Scales of Two Closely Related Snake Species (Animals : an open access journal from MDPI · 2025Article
- The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation.BMC genomics · 2024Review
- The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation.bioRxiv : the preprint server for biology · 2024Article
- What Makes a Mimic? Orange, Red, and Black Color Production in the Mimic Poison Frog (Ranitomeya imitator).Genome biology and evolution · 2024Article
- Correlated evolution of conspicuous colouration and burrowing in crayfish.Proceedings. Biological sciences · 2024Article
- Multiple Routes to Color Convergence in a Radiation of Neotropical Poison Frogs.Systematic biology · 2023Article
- Color polymorphism in the Cuban endemic livebearing fishEcology and evolution · 2023Article
- Article
- Factors determining the dorsal coloration pattern of aposematic salamanders.Scientific reports · 2022Article
- Ionizing radiation and melanism in Chornobyl tree frogs.Evolutionary applications · 2022Article
- Gene expression in male and female stickleback from populations with convergent and divergent throat coloration.Ecology and evolution · 2022Article
- Population genetic differentiation and genomic signatures of adaptation to climate in an abundant lizard.Heredity · 2022Article
- Article
- Pterin-based pigmentation in animals.Biology letters · 2021Article
- The genomics of mimicry: Gene expression throughout development provides insights into convergent and divergent phenotypes in a Müllerian mimicry system.Molecular ecology · 2021Article
- Ultraviolet components offer minimal contrast enhancement to an aposematic signal.Ecology and evolution · 2020Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundColor and pattern phenotypes have clear implications for survival and reproduction in many species. However, the mechanisms that produce this coloration are still poorly characterized, especially at the genomic level. Here we have taken a transcriptomics-based approach to elucidate the underlying genetic mechanisms affecting color and pattern in a highly polytypic poison frog. We sequenced RNA from the skin from four different color morphs during the final stage of metamorphosis and assembled a de novo transcriptome. We then investigated differential gene expression, with an emphasis on examining candidate color genes from other taxa.
resultsOverall, we found differential expression of a suite of genes that control melanogenesis, melanocyte differentiation, and melanocyte proliferation (e.g., tyrp1, lef1, leo1, and mitf) as well as several differentially expressed genes involved in purine synthesis and iridophore development (e.g., arfgap1, arfgap2, airc, and gart).
conclusionsOur results provide evidence that several gene networks known to affect color and pattern in vertebrates play a role in color and pattern variation in this species of poison frog.
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