ReviewBioengineering (Basel, Switzerland)2019
Polyhydroxyalkanoate Biosynthesis at the Edge of Water Activitiy-Haloarchaea as Biopolyester Factories.
Review in Bioengineering (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed.
- Article
- Polyhydroxyalkanoates as multifaceted biopolymers: an eco-friendly alternative to conventional plastics.RSC advances · 2026Review
- Isolation and Preliminary Characterization of Salt-Tolerant Polyhydroxyalkanoate-Producing Bacteria from the Hon Khoi Saltern, Khanh Hoa, Vietnam.Microorganisms · 2026Article
- Recent Advances in Understanding Bio-Compounds from Haloarchaea.Journal of microbiology and biotechnology · 2026Review
- Exploring Lemon Industry By-Products for Polyhydroxyalkanoate Production: Comparative Performances ofPolymers · 2026Article
- Molecular adaptations and engineering of extremophiles for synthetic biology and biotechnological applications.Frontiers in microbiology · 2026Review
- A Review of Bioelectrochemical Strategies for Enhanced Polyhydroxyalkanoate Production.Bioengineering (Basel, Switzerland) · 2025Review
- Advanced Strategies for Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Production: PHA Synthase Homologous Overexpression in the ExtremophileMarine drugs · 2025Article
- Review
- Microbial diversity in polyextreme salt flats and their potential applications.Environmental science and pollution research international · 2024Review
- Microbial communities in the Dead Sea and their potential biotechnological applications.Communicative & integrative biology · 2024Review
- Trends in PHA Production by Microbially Diverse and Functionally Distinct Communities.Microbial ecology · 2023Review
- Characterization of Polyhydroxybutyrate, PHB, Synthesized by Newly Isolated HaloarchaeaMolecules (Basel, Switzerland) · 2022Article
- Biosynthesis and Properties of a P(3HB-Polymers · 2022Article
- Assessment of the efficacy of slow-release formulations of the tribenuron-methyl herbicide in field-grown spring wheat.Environmental science and pollution research international · 2022Article
- Exploitation of wasted bread as substrate for polyhydroxyalkanoates production through the use ofFrontiers in microbiology · 2022Article
- Analysis of Polyhydroxyalkanoates Granules inPolymers · 2021Article
- Laser Processing of Polymer Films Fabricated from PHAs Differing in Their Monomer Composition.Polymers · 2021Article
- Review
- Metabolic potential of the moderate halophile Yangia sp. ND199 for co-production of polyhydroxyalkanoates and exopolysaccharides.MicrobiologyOpen · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haloarchaea, the extremely halophilic branch of the Archaea domain, encompass a steadily increasing number of genera and associated species which accumulate polyhydroxyalkanoate biopolyesters in their cytoplasm. Such ancient organisms, which thrive in highly challenging, often hostile habitats characterized by salinities between 100 and 300 g/L NaCl, have the potential to outperform established polyhydroxyalkanoate production strains. As detailed in the review, this optimization presents due to multifarious reasons, including: cultivation setups at extreme salinities can be performed at minimized sterility precautions by excluding the growth of microbial contaminants; the high inner-osmotic pressure in haloarchaea cells facilitates the recovery of intracellular biopolyester granules by cell disintegration in hypo-osmotic media; many haloarchaea utilize carbon-rich waste streams as main substrates for growth and polyhydroxyalkanoate biosynthesis, which allows coupling polyhydroxyalkanoate production with bio-economic waste management; finally, in many cases, haloarchaea are reported to produce copolyesters from structurally unrelated inexpensive substrates, and polyhydroxyalkanoate biosynthesis often occurs in parallel to the production of additional marketable bio-products like pigments or polysaccharides. This review summarizes the current knowledge about polyhydroxyalkanoate production by diverse haloarchaea; this covers the detection of new haloarchaea producing polyhydroxyalkanoates, understanding the genetic and enzymatic particularities of such organisms, kinetic aspects, material characterization, upscaling and techno-economic and life cycle assessment.
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