Evidence map›Paper›PMID 30995790›Full record

ArticleNutrients2019

The Chinese Herbal Formula PAPZ Ameliorates Behavioral Abnormalities in Depressive Mice.

Huiling Chen, Qing Huang, Shunjia Zhang, Kaiqiang Hu, Wenxiang Xiong, Lingyun Xiao, Renhuai Cong, Qingfei Liu, Zhao Wang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. History and main research of psychoneuroimmunology in China.Brain, behavior, & immunity - health · 2022
    Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Huiling ChenMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. chenhl16@mails.tsinghua.edu.cn.
Qing HuangMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. qinghuangfgh@163.com.
Shunjia ZhangMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. shunjia.zhang@yale.edu.
Kaiqiang HuMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. hkq15@mails.tsinghua.edu.cn.
Wenxiang XiongMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. xiongwxiang@163.com.
Lingyun XiaoResearch & Development Centre, Infinitus (China) Company Ltd., Guangzhou 510663, China. xiaolingyun12@126.com.
Renhuai CongResearch & Development Centre, Infinitus (China) Company Ltd., Guangzhou 510663, China. Renhuai.Cong@infinitus-int.com.
Qingfei LiuMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. liuqf@tsinghua.edu.cn.
Zhao WangMOE Key Laboratory of Protein Science, School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China. zwang@tsinghua.edu.cn.
Tsinghua University · CNInfinitus (China) · CNYale University · US

Funding

The European Union's Horizon 2020 Research and Innovation Program 633589The Key International S&T Cooperation Program of China 2016YFE113700The National Key R&D Program of China 2018YFD0400204The National Natural Science Foundation of China 81471396, 81871095
6 · The paper itself

Abstract

Major depressive disorder (MDD) is a chronic mental disorder characterized by mixed symptoms and complex pathogenesis. With long history of practical application, traditional Chinese medicine (TCM) offers many herbs for the treatment and rehabilitation of chronic disease. In this study, we developed a modified Chinese herbal formula using

Indexed as

MagnoliopsidaPhytotherapyAngelica sinensisAnimalsAntidepressive AgentsAntioxidantsBehavior, AnimalBrain-Derived Neurotrophic FactorCorticosteroneDepressionDisease Models, AnimalDrugs, Chinese HerbalHippocampusMajor Depressive DisorderMaleMalondialdehydeAntidepressive AgentsAntioxidantsBrain-Derived Neurotrophic FactorCorticosteroneDrugs, Chinese HerbalMalondialdehydeSuperoxide DismutaseBDNFChinese herbal formulacorticosteronemajor depressive disorderoxidative stress

Identifiers

PMID30995790
PMCPMC6521158
OpenAlexW2936166349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.