Evidence map›Paper›PMID 30995769›Full record

ArticleInternational journal of molecular sciences2019

Calcium Activity Dynamics Correlate with Neuronal Phenotype at a Single Cell Level and in a Threshold-Dependent Manner.

Sudip Paudel, Eileen Ablondi, Morgan Sehdev, John Marken, Andrew Halleran, Atiqur Rahman, Peter Kemper, Margaret S Saha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sudip PaudelDepartment of Biology, College of William and Mary, Williamsburg, VA 23185, USA. spaudel@email.wm.edu.ORCID 0000-0003-4502-8405
Eileen AblondiDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University, Boston, MA 02115, USA. efablondi@g.harvard.edu.
Morgan SehdevHarvard Medical School, Harvard University, Boston, MA 02115, USA. msehdev@email.wm.edu.
John MarkenDepartment of Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA. jmarken@caltech.edu.ORCID 0000-0001-9696-088X
Andrew HalleranDepartment of Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA. halleran@caltech.edu.
Atiqur RahmanDepartment of Computer Science, College of William and Mary, Williamsburg, VA 23185, USA. mrahman@email.wm.edu.
Peter KemperDepartment of Computer Science, College of William and Mary, Williamsburg, VA 23185, USA. kemper@cs.wm.edu.
Margaret S SahaDepartment of Biology, College of William and Mary, Williamsburg, VA 23185, USA. mssaha@wm.edu.ORCID 0000-0003-0096-2667
William & Mary · USCalifornia Institute of Technology · USHarvard University · US

Funding

Molecular Analysis of Early Neural PlasticityR15HD096415 · NICHD · COLLEGE OF WILLIAM AND MARY · PI SAHA, MARGARET S · 2018 to 2018
$402k
NICHD NIH HHS R15 HD096415NIH HHS 1R15NS067566-01: 1R15HD077624-01; 1R15HD096415-01
6 · The paper itself

Abstract

Calcium is a ubiquitous signaling molecule that plays a vital role in many physiological processes. Recent work has shown that calcium activity is especially critical in vertebrate neural development. Here, we investigated if calcium activity and neuronal phenotype are correlated only on a population level or on the level of single cells. Using

Indexed as

AnimalsCalciumCells, CulturedFemaleGene Expression Regulation, DevelopmentalMaleNeural PlateNeuronsOptical ImagingPhenotypeSingle-Cell AnalysisXenopus laevisCalciumCa2+calciumcalcium activitydevelopmentembryonervous systemneural developmentsox2tubb2bXenopus

Identifiers

PMID30995769
PMCPMC6515432
OpenAlexW2939775300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.