Evidence map›Paper›PMID 30995767›Full record

ReviewInternational journal of molecular sciences2019

PRRs and NB-LRRs: From Signal Perception to Activation of Plant Innate Immunity.

Ali Noman, Muhammad Aqeel, Yonggen Lou

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
17.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 96 citations in OpenAlex.

  1. Article
  2. Article
  3. TheAntioxidants (Basel, Switzerland) · 2026
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  4. Review
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  6. miRNA-Mediated Regulation ofInternational journal of molecular sciences · 2025
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  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Mining of Minor Disease Resistance Genes inInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Parallel repair mechanisms in plants and animals.Disease models & mechanisms · 2023
    Article
  17. Article
  18. Article
  19. Analysis of theGenes · 2022
    Article
  20. Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Ali NomanInstitute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310027, China. alinoman@gcuf.edu.pk.ORCID 0000-0002-4159-199X
Muhammad AqeelState Key Laboratory of Grassland Agro-ecosystems, School of Life Science, Lanzhou University, Lanzhou 730000, China. aqeelbutt99@gmail.com.ORCID 0000-0003-0690-4783
Yonggen LouInstitute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310027, China. yglou@zju.edu.cn.ORCID 000-0002-3262-6134
Government College University, Faisalabad · PKLanzhou University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To ward off pathogens and pests, plants use a sophisticated immune system. They use pattern-recognition receptors (PRRs), as well as nucleotide-binding and leucine-rich repeat (NB-LRR) domains, for detecting nonindigenous molecular signatures from pathogens. Plant PRRs induce local and systemic immunity. Plasma-membrane-localized PRRs are the main components of multiprotein complexes having additional transmembrane and cytosolic kinases. Topical research involving proteins and their interactive partners, along with transcriptional and posttranscriptional regulation, has extended our understanding of R-gene-mediated plant immunity. The unique LRR domain conformation helps in the best utilization of a surface area and essentially mediates protein-protein interactions. Genome-wide analyses of inter- and intraspecies PRRs and NB-LRRs offer innovative information about their working and evolution. We reviewed plant immune responses with relevance to PRRs and NB-LRRs. This article focuses on the significant functional diversity, pathogen-recognition mechanisms, and subcellular compartmentalization of plant PRRs and NB-LRRs. We highlight the potential biotechnological application of PRRs and NB-LRRs to enhance broad-spectrum disease resistance in crops.

Indexed as

Plant ImmunityCrops, AgriculturalImmunity, InnateNLR ProteinsPlant DiseasesPlant ProteinsPlantsReceptors, Pattern RecognitionNLR ProteinsPlant ProteinsReceptors, Pattern RecognitiondefensePAMPspathogenesisplantstranscriptional activity

Identifiers

PMID30995767
PMCPMC6514886
OpenAlexW2939746267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.