Evidence map›Paper›PMID 30995761›Full record

ArticlePharmaceutics2019

Design of Poly(lactic-

Haitao Yang, Jing Li, Sravan Kumar Patel, Kenneth E Palmer, Brid Devlin, Lisa C Rohan

Abstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Trial
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  10. Article
  11. Nanoscale advances · 2024
    Article
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  13. Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haitao YangDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA. hyang96@its.jnj.com.
Jing LiDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA. jil132@pitt.edu.
Sravan Kumar PatelDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA. patels10@mwri.magee.edu.ORCID 0000-0002-1235-3458
Kenneth E PalmerCenter for Predictive Medicine and Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA. kenneth.palmer@louisville.edu.
Brid DevlinInternational Partnership for Microbicides, Silver Spring, MD 20910, USA. bdevlin@ipmglobal.org.
Lisa C RohanDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA. rohanlc@upmc.com.

Funding

Project 3: PREVENT: A first-in-human clinical trial of Griffithsin, an HIV entryU19AI113182 · NIAID · UNIVERSITY OF LOUISVILLE · PI BRAND, RHONDA METTER · 2014 to 2018
$14.8M
Pharmaceutical and Regulatory CoreU19AI082639 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ROHAN, LISA CENCIA · 2010 to 2014
$13.0M
Building Research Careers in Women's HealthK12HD043441 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SADOVSKY, YOEL · 2002 to 2023
$10.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development K12HD043441National Institute of Allergy and Infectious Diseases U19AI082639National Institute of Allergy and Infectious Diseases U19AI113182
6 · The paper itself

Abstract

Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-

Indexed as

co-deliverycombination ARVsHIVmicrobicidesPLGA nanoparticlessustained releasesynergism

Identifiers

PMID30995761
PMCPMC6523646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.