Evidence map›Paper›PMID 30995742›Full record

ArticleCancers2019

Frequent Occurrence of

Philipp Jansen, Ioana Cosgarea, Rajmohan Murali, Inga Möller, Antje Sucker, Cindy Franklin, Annette Paschen, Anne Zaremba, Titus J Brinker, Ingo Stoffels and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Expression ofCells · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Philipp JansenDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. philipp.jansen@uk-essen.de.ORCID 0000-0003-3139-2118
Ioana CosgareaDermatological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. ioana.cosgarea@newcastle.ac.uk.
Rajmohan MuraliDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. muralir@mskcc.org.
Inga MöllerDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. inga.moeller@uk-essen.de.
Antje SuckerDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. antje.sucker@uk-essen.de.
Cindy FranklinDepartment of Dermatology, University of Cologne, 50937 Cologne, Germany. cindy.franklin@uk-koeln.de.
Annette PaschenDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. annette.paschen@uk-essen.de.
Anne ZarembaDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. anne.zaremba@uk-essen.de.
Titus J BrinkerDepartment of Dermatology, University Hospital Heidelberg, 69120 Heidelberg, Germany. titus.brinker@nct-heidelberg.de.
Ingo StoffelsDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. ingo.stoffels@uk-essen.de.ORCID 0000-0003-0111-1303
Dirk SchadendorfDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. dirk.schadendorf@uk-essen.de.
Joachim KlodeDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. joachim.klode@uk-essen.de.
Eva HadaschikDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. eva.hadaschik@uk-essen.de.
Klaus G GriewankDepartment of Dermatology, Venerology and Allergology, University Hospital Essen, 45147 Essen, Germany. Klaus.griewank@uk-essen.de.ORCID 0000-0003-3899-9449
German Cancer Research Center · DEMemorial Sloan Kettering Cancer Center · USNewcastle University · GBUniversity of Cologne · DE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Acral naevi are benign melanocytic tumors occurring at acral sites. Occasionally they can progress to become malignant tumors (melanomas). The genetics of acral naevi have not been assessed in larger studies. In our study, a large cohort of 130 acral naevi was screened for gene mutations known to be important in other naevi and melanoma subtypes by targeted next-generation sequencing. Mutation status was correlated with clinicopathological parameters. Frequent mutations in genes activating the MAP kinase pathway were identified, including

Indexed as

acraldermatologygeneticsmelanomanaevi

Identifiers

PMID30995742
PMCPMC6520878
OpenAlexW2940200713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.