Evidence map›Paper›PMID 30995715›Full record

ReviewInternational journal of molecular sciences2019

LKB1 and Tumor Metabolism: The Interplay of Immune and Angiogenic Microenvironment in Lung Cancer.

Laura Bonanno, Elisabetta Zulato, Alberto Pavan, Ilaria Attili, Giulia Pasello, PierFranco Conte, Stefano Indraccolo

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Genomic alterations and their correlation with metabolic-related genes in lung cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  5. Article
  6. Pan-Cancer Computational Analysis of RKIP (International journal of molecular sciences · 2025
    Article
  7. mBio · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Metabolic heterogeneity in early-stage lung adenocarcinoma revealed by RNA-seq and scRNA-seq.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  13. The role of the SNF1 signaling pathway in the growth of Saccharomyces cerevisiae in different carbon and nitrogen sources.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Role of AMPK in autophagy.Frontiers in physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura BonannoMedical Oncology 2, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. laura.bonanno@iov.veneto.it.ORCID 0000-0002-4810-7136
Elisabetta ZulatoImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. elisabetta.zulato@iov.veneto.it.
Alberto PavanMedical Oncology 2, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. alberto.pavan@iov.veneto.it.
Ilaria AttiliMedical Oncology 2, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. ilaria.attili@iov.veneto.it.ORCID 0000-0003-1333-6622
Giulia PaselloMedical Oncology 2, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. giulia.pasello@iov.veneto.it.
PierFranco ConteMedical Oncology 2, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. pierfranco.conte@unipd.it.
Stefano IndraccoloImmunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV- IRCCS, 35128 Padova, Italy. stefano.indraccolo@iov.veneto.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver kinase B1 (

Indexed as

Tumor MicroenvironmentAMP-Activated Protein Kinase KinasesAnimalsAntineoplastic AgentsHumansImmune ToleranceImmunotherapyLungLung NeoplasmsNeovascularization, PathologicProtein Serine-Threonine KinasesAMP-Activated Protein Kinase KinasesAntineoplastic AgentsProtein Serine-Threonine KinasesSTK11 protein, humanimmunotherapyLKB1lung cancertreatment responsetumor angiogenesistumor metabolismtumor microenvironment

Identifiers

PMID30995715
PMCPMC6514929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.