Evidence map›Paper›PMID 30995230›Full record

Observational studyPloS one2019

Assessing the causes of under-five mortality and proportion associated with pneumococcal diseases in Cameroon. A case-finding retrospective observational study: 2006-2012.

John Njuma Libwea, Sandrine Rachel Bebey Kingue, Nadesh Taku Ashukem, Marie Kobela, Angeline Boula, Koulla-Shiro Sinata, Paul Koki Ndombo

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

John Njuma LibweaFaculty of Social Sciences, Health Sciences Unit, Tampere University, Tampere, Finland.ORCID 0000-0001-8284-3236
Sandrine Rachel Bebey KingueMother & Child Centre (MCH), Chantal Biya Foundation, Yaoundé, Cameroon.
Nadesh Taku AshukemMother & Child Centre (MCH), Chantal Biya Foundation, Yaoundé, Cameroon.ORCID 0000-0002-6514-6743
Marie KobelaExpanded Programme on Immunization, Yaoundé, Cameroon.
Angeline BoulaMother & Child Centre (MCH), Chantal Biya Foundation, Yaoundé, Cameroon.
Koulla-Shiro SinataFaculty of Sciences, Department of Microbiology, University of Buea, Buea, Cameroon.
Paul Koki NdomboMother & Child Centre (MCH), Chantal Biya Foundation, Yaoundé, Cameroon.
Université de Yaoundé I · CMUniversity of Buea · CMCentre International De Reference Chantal Biya · CMTampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVital registration data outlining causes of deaths (CoD) are important for a sustainable health system, targeted interventions and other relevant policies. There is data paucity on vital registration systems in developing countries. We assessed the leading causes and proportions of under-five deaths, and particularly those related to pneumococcal infections in Yaoundé, Cameroon, using hospital registration data.

methodsA retrospective case-finding observational study design was used to access and identify data on 817 death cases in children under-five years of age recorded in health facilities in Yaoundé, within the period January 1, 2006 and December 31, 2012. Patients' files were randomly selected and needed information including demographic data, date of admission, clinical and laboratory diagnosis, principal and/or underlying causes of death were abstracted into structured case report forms. The International Classification of Diseases and Clinical Modifications 10th revision (ICD-10-CM) codes (ICD10Data.com 2017 edition) were used to classify the different CoD, retrospectively. Ascertainment of CoD was based on medical report and estimates were done using the Kaplan-Meier procedure and descriptive statistics.

resultsOf the 817 death records assessed, malaria was the leading CoD and was responsible for 17.5% of cases. Meningitis was the second largest CoD with 11.0%; followed by sepsis (10.0%), Streptococcus pneumoniae infections (8.3%), malnutrition (8.3%), gastro-enteritis / diarrhoea (6.2%), anaemia (6.1%) and HIV (3.5%), respectively.

conclusionThe main CoD in this population are either treatable or vaccine-preventable; a trend consistent with previous reports across developing countries. Besides, the health effects from non-communicable infections should not be neglected. Therefore, scaling-up measures to reduce causes of under-five deaths will demand sustainable efforts to enhance both treatment and disease prevention strategies, to avoid a decline in the progress towards reducing under-five deaths by 2/3 from the 1990 baseline.

Indexed as

Child MortalityCameroonCause of DeathChild, PreschoolFemaleHumansInfantMalariaMalePneumococcal Infections

Identifiers

PMID30995230
PMCPMC6469747
OpenAlexW2939771133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.