Evidence map›Paper›PMID 30995069›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach.

Erik A Jensen, Kevin Dysart, Marie G Gantz, Scott McDonald, Nicolas A Bamat, Martin Keszler, Haresh Kirpalani, Matthew M Laughon, Brenda B Poindexter, Andrea F Duncan and 3 more

8 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 719 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
719citing papers in PubMed, 5 pooled it
64.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04184648 completednot on this mapstarted 2020, after this paper: background citation

Clinical Study on Comparative Diagnostic Criteria of Bronchopulmonary Dysplasia in Premature Infants

TypeobservationalSponsorWang JianhuiRan2020 to 2022Enrolled322ConditionsBronchopulmonary DysplasiaArmsno interventions
NCT04372953 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).

TypeinterventionalSponsorMurdoch Childrens Research InstituteRan2021 to 2028Enrolled906ConditionsLung Injury, Preterm BirthArmsPositive End-Expiratory Pressure (PEEP)
NCT04662151 phase1completednot on this mapstarted 2021, after this paper: background citation

A Phase 1b, Randomized, Blinded, Dose-Determined Study Evaluating the Safety and Tolerability Profile of Intervention With AT-100 (rhSP-D) in Preterm Neonates at High Risk for the Development of Bronchopulmonary Dysplasia (BPD)

TypeinterventionalSponsorAirway Therapeutics, Inc.Ran2021 to 2024Enrolled37ConditionsBronchopulmonary DysplasiaArmsAT-100, Air-sham
NCT04971694 completednot on this mapstarted 2021, after this paper: background citation

A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants At Risk for Bronchopulmonary Dysplasia (BPD) At a Single Center Neonatal Intensive Care Unit

TypeobservationalSponsorPediatrixRan2021 to 2024Enrolled175ConditionsBPD - Bronchopulmonary DysplasiaArmsNo interventions or procedures
NCT05235399 completednot on this mapstarted 2022, after this paper: background citation

Exploring Right vEntricular Function Applicability in a Prediction mOdel to Identify pReterm infanTs With Early BronchoPulmonary Dysplasia (REPORT - BPD Study): a Mixed Methods Observational Cohort Feasibility Study

TypeobservationalSponsorUniversity Hospital Plymouth NHS TrustRan2022 to 2023Enrolled40ConditionsBronchopulmonary Dysplasia, Right Ventricular Dysfunction, In the Perinatal PeriodArmsEcho scans
NCT05915806 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Enteral Supplementation With High-dose Docosahexaenoic Acid on the Risk for Bronchopulmonary Dysplasia in Very Preterm Infants: A Collaborative Study Protocol for an Individual Participant Data Meta-analysis

TypeinterventionalSponsorCHU de Quebec-Universite LavalRan2023 to 2026Enrolled1,801ConditionsBronchopulmonary Dysplasia, Child Development, Neonatal and Perinatal ConditionsArmsHigh-dose DHA, Control
NCT06290232 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Fetoscopic Laser Photocoagulation in Management of Vasa Previa - FLUMEN Study

TypeinterventionalSponsorBoston Children's HospitalRan2026 to 2028Enrolled0ConditionsVasa Previa, Pregnancy Complications, Maternal, ProcedureArmsFetoscopic Laser Photocoagulation
NCT07652684 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Enteral Lipid Supplementation and Bronchoplumonary Dysplasia of Premature Infants: A Randomized Controlled Trial (The PRELUDE Trial)

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2025 to 2027Enrolled74ConditionsBronchopulmonary Dysplasia (BPD)ArmsEnteral supplementation with ARA and DHA (in a 2:1 ratio) in addition to standard care and feeding, Standard care and feeding
3 · Its place in the literature

Who cites it

719 citing papers in PubMed, 5 syntheses or guidelines pooled it, 1,129 citations in OpenAlex.

  1. Pooled it
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  3. Platelet transfusion thresholds for thrombocytopenic infants.The Cochrane database of systematic reviews · 2026
    Pooled it
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  5. Systemic steroids and bronchopulmonary dysplasia: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Pooled it
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  18. Sixty golden minutes: a quality improvement bundle reduces morbidities in at-risk preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  19. Article
  20. Comparison of growth and morbidity outcomes in preterm infants using two different intravenous lipid emulsions.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article

659 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Erik A JensenDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Kevin DysartDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Marie G GantzBiostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina.
Scott McDonaldBiostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina.
Nicolas A BamatDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-6427-093X
Martin KeszlerDepartment of Pediatrics, Women and Infant's Hospital of Rhode Island, Brown University, Providence, Rhode Island.
Haresh KirpalaniDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Matthew M LaughonDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Brenda B PoindexterPerinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Andrea F DuncanDivision of Neonatology, Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, Texas; and.
Bradley A YoderDivision of Neonatology, University of Utah, Salt Lake City, Utah.
Eric C EichenwaldDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Sara B DeMauroDivision of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania.
Children's Hospital of Philadelphia · USRTI International · USBrown University · USCincinnati Children's Hospital Medical Center · USThe University of Texas Health Science Center at Houston · USUniversity of North Carolina at Chapel Hill · USUniversity of Utah · US

Funding

NICHD Neonatal Research Network -- Cincinnati Clinical CenterUG1HD027853 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI STEPHANIE L MERHAR · 2016 to 2026
$3.7M
Clinical Center for NICHD/Neonatal Research NetworkUG1HD068244 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI Sara Bonamo DeMauro, Eric C Eichenwald · 2016 to 2026
$3.6M
NICHD Cooperative Multicenter Neonatal Research Network - Utah CenterUG1HD087226 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ROBIN K OHLS · 2016 to 2026
$3.3M
NICHD Neonatal Research Network - Stanford UniversityUG1HD027880 · NICHD · STANFORD UNIVERSITY · PI Valerie Chock · 2016 to 2026
$3.3M
NICHD Neonatal Research NetworkUG1HD027904 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI MARON, JILL LAMANNA · 2016 to 2024
$2.1M
Multicenter Network of Neonatal Intensive Care Units-University of Texas at Houston (UT Houston) Clinical CenterUG1HD087229 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TYSON, JON E. · 2016 to 2022
$2.0M
Microbiome of the Airway and the Risk for Bronchopulmonary Dysplasia in the Lungs of Extreme Preterms: The MARBLE StudyK23HL136843 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI JENSEN, ERIK ALLEN · 2018 to 2022
$819k
NHLBI NIH HHS K23 HL136843NICHD NIH HHS UG1 HD027853NICHD NIH HHS UG1 HD027880NICHD NIH HHS UG1 HD027904NICHD NIH HHS UG1 HD068244NICHD NIH HHS UG1 HD087226NICHD NIH HHS UG1 HD087229
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bronchopulmonary DysplasiaEvidence-Based MedicineFemaleHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightMalePediatricsUnited Statesinfant chronic lung diseasemechanical ventilationsupplemental oxygen

Identifiers

PMID30995069
PMCPMC6775872
OpenAlexW2935685937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.