Evidence map›Paper›PMID 30995019›Full record

ReviewChemical reviews2019

Nanowired Bioelectric Interfaces.

Bozhi Tian, Charles M Lieber

Abstract readReview
In one paragraph

Review in Chemical reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. An AI Agent for cell-type specific brain computer interfaces.bioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Bio-hybrid electronic and photonic devices.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
  14. Article
  15. Semi-Implantable Bioelectronics.Nano-micro letters · 2022
    Review
  16. Review
  17. Review
  18. Review
  19. Biomedical Implants with Charge-Transfer Monitoring and Regulating Abilities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bozhi TianDepartment of Chemistry , The University of Chicago , Chicago , Illinois 60637 , United States.ORCID 0000-0003-0593-0023
Charles M LieberDepartment of Chemistry and Chemical Biology , Harvard University , Cambridge , Massachusetts 02138 , United States.ORCID 0000-0002-6660-2456

Funding

Syringe-Injectable Mesh Electronics for Seamless Integration with the Central Nervous SystemDP1EB025835 · NIBIB · HARVARD UNIVERSITY · PI LIEBER, CHARLES M · 2017 to 2019
$3.5M
Silicon-based Injectable Micro-gels for Non-genetic and Wireless Modulation of Neurons, Cardiomyocytes and Neuromuscular SystemDP2NS101488 · NINDS · UNIVERSITY OF CHICAGO · PI TIAN, BOZHI · 2016 to 2016
$2.4M
Syringe Injectable Electronics Platform for Chronic Mapping and Modulation of Neural Circuits in AddictionR21DA043985 · NIDA · HARVARD UNIVERSITY · PI LIEBER, CHARLES M · 2017 to 2018
$436k
NIBIB NIH HHS DP1 EB025835NIDA NIH HHS R21 DA043985NINDS NIH HHS DP2 NS101488
6 · The paper itself

Abstract

Biological systems have evolved biochemical, electrical, mechanical, and genetic networks to perform essential functions across various length and time scales. High-aspect-ratio biological nanowires, such as bacterial pili and neurites, mediate many of the interactions and homeostasis in and between these networks. Synthetic materials designed to mimic the structure of biological nanowires could also incorporate similar functional properties, and exploiting this structure-function relationship has already proved fruitful in designing biointerfaces. Semiconductor nanowires are a particularly promising class of synthetic nanowires for biointerfaces, given (1) their unique optical and electronic properties and (2) their high degree of synthetic control and versatility. These characteristics enable fabrication of a variety of electronic and photonic nanowire devices, allowing for the formation of well-defined, functional bioelectric interfaces at the biomolecular level to the whole-organ level. In this Focus Review, we first discuss the history of bioelectric interfaces with semiconductor nanowires. We next highlight several important, endogenous biological nanowires and use these as a framework to categorize semiconductor nanowire-based biointerfaces. Within this framework we then review the fundamentals of bioelectric interfaces with semiconductor nanowires and comment on both material choice and device design to form biointerfaces spanning multiple length scales. We conclude with a discussion of areas with the potential for greatest impact using semiconductor nanowire-enabled biointerfaces in the future.

Indexed as

Electrical Equipment and SuppliesProstheses and ImplantsAnimalsBacteriaBrain-Computer InterfacesHumansNanowiresSemiconductorsTransistors, Electronic

Identifiers

PMID30995019
PMCPMC6693975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.