ArticleJournal of magnetic resonance imaging : JMRI2019
Vessel wall and lumen characteristics with age in healthy participants using 3T intracranial vessel wall magnetic resonance imaging.
Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Deep learning-based basilar artery wall and lumen segmentation from 1-mm MR vessel wall imaging.Scientific reports · 2026Article
- High-risk characteristics of recurrent ischemic stroke after intensive medical management for 6-month follow-up: a histogram study on vessel wall MRI.European radiology · 2025Observational
- Statistical analysis of the measured strength parameters of the fresh main intracranial arteries.Frontiers in bioengineering and biotechnology · 2025Article
- The association between basilar artery wall thickness and posterior circulation ischemic stroke: insights from high-resolution vascular wall imaging in subclinical atherosclerosis.Frontiers in neurology · 2025Article
- Assessment of Post-COVID-19 Changes in Brain-Clinical and Imaging Evaluation Using MRI Vessel Wall Imaging and Complementary MRI Methods.Journal of clinical medicine · 2024Article
- Clinical consequence of vessel perforations during endovascular treatment of acute ischemic stroke.Neuroradiology · 2024Article
- Article
- Reference Values of Cerebral Artery Diameters of the Anterior Circulation by Digital Subtraction Angiography: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2022Article
- The cerebral artery in cynomolgus monkeys (Macaca fascicularis).Experimental animals · 2022Article
- Application and interpretation of vessel wall magnetic resonance imaging for intracranial atherosclerosis: a narrative review.Annals of translational medicine · 2022Review
- Plaque Characteristics in Young Adults With Symptomatic Intracranial Atherosclerotic Stenosis: A Preliminary Study.Frontiers in neurology · 2022Article
- Sex Differences in Intracranial Atherosclerotic Plaques Among Patients With Ischemic Stroke.Frontiers in cardiovascular medicine · 2022Article
- Quantification of intracranial arterial stenotic degree evaluated by high-resolution vessel wall imaging and time-of-flight MR angiography: reproducibility, and diagnostic agreement with DSA.European radiology · 2021Article
- A cross-sectional, case-control study of intracranial arterial wall thickness and complete blood count measures in sickle cell disease.British journal of haematology · 2021Article
- Vessel Wall and Lumen Features in North American Moyamoya Patients.Clinical neuroradiology · 2020Article
- Automated Grading of Cerebral Vasospasm to Standardize Computed Tomography Angiography Examinations After Subarachnoid Hemorrhage.Frontiers in neurology · 2020Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundIntracranial vessel wall imaging (VWI) at a clinical field strength of 3T has become more widely available. However, how vessel measurements change with age and sex, over an age range spanning a typical lifespan, are needed. PURPOSE/HYPOTHESIS: To assess for identifiable changes in arterial wall thickness, outer vessel wall diameter, and lumen diameter with age cross-sectionally in healthy controls without cerebrovascular disease risk factors at the spatial resolution afforded by currently recommended 3T VWI approaches. STUDY TYPE: Prospective. POPULATION/SUBJECTS: Healthy subjects (n = 82; age = 8-79 years). FIELD STRENGTH/SEQUENCE: 3T intracranial VWI, angiography, and T ASSESSMENT: Two readers measured lumen and outer wall diameters of the supraclinoid internal carotid artery (ICA) and distal basilar artery. Wall thickness and intraclass correlation coefficients (ICCs) were calculated. STATISTICAL TESTS: Separate linear regressions were performed to understand the relationship between wall measurements (lumen diameter, outer vessel wall diameter, and wall thickness) and age, gender, side (left or right); significance: two-sided P < 0.05.
resultsReaders showed excellent agreement for lumen and outer wall diameters (ICC 0.83-094). Linear regression of supraclinoid ICA wall measurements showed a statistically significant increase in wall thickness (P = 0.00051) and outer vessel wall diameter (P = 0.030) with age. ICA lumen and outer vessel wall diameters were statistically greater in males vs. females (lumen diameter 3.69 ± 0.41 vs. 3.54 ± 0.35 mm, P = 0.026; outer wall diameter 5.78 ± 0.52 vs. 5.56 ± 0.44 mm, P = 0.0089) with a trend toward increase in wall thickness (1.05 ± 0.12 vs. 1.01 ± 0.10 mm, P = 0.055). No significant difference was found in basilar artery wall thickness (P = 0.45, P = 0.72), lumen diameter (P = 0.15, P = 0.42), or outer vessel wall diameter (P = 0.34, P = 0.41) with age or gender, respectively. DATA
conclusionIntracranial vessel wall measurements were shown to be consistent between readers. At the available spatial resolution of 3T intracranial VWI sequences, supraclinoid ICA vessel wall thickness and outer vessel wall diameter appear to mildly increase with age. There was no detectable change in basilar artery vessel wall characteristics with age. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2019;50:1452-1460.
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