Evidence map›Paper›PMID 30994775›Full record

Trial reportJournal of applied oral science : revista FOB2019

Microbial species associated with dental caries found in saliva and in situ after use of self-ligating and conventional brackets.

Ana Zilda Nazar Bergamo, Mirian Aiko Nakane Matsumoto, Cássio do Nascimento, Marcela Cristina Damião Andrucioli, Fábio Lourenço Romano, Raquel Assed Bezerra Silva, Léa Assed Bezerra Silva, Paulo Nelson-Filho

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied oral science : revista FOB, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. In vitro study of structural and mechanical properties of latex and non-latex intermaxillary orthodontic elastics.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ana Zilda Nazar BergamoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-3313-2152
Mirian Aiko Nakane MatsumotoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0001-8559-8715
Cássio do NascimentoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Materiais Dentários e Prótese, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-2220-0148
Marcela Cristina Damião AndrucioliUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-4675-5671
Fábio Lourenço RomanoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-1419-3520
Raquel Assed Bezerra SilvaUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0002-0230-1347
Léa Assed Bezerra SilvaUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0003-1179-0098
Paulo Nelson-FilhoUniversidade de São Paulo, Faculdade de Odontologia de Ribeirão Preto, Departamento de Clinica Infantil, Ribeirão Preto, São Paulo, Brasil.ORCID http://orcid.org/0000-0001-8802-6480
Universidade de Ribeirão Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEnamel demineralization is among the main topics of interest in the orthodontic field. Self-ligating brackets have been regarded as advantageous in this aspect. The aim of this study was to evaluate the break homeostasis in the oral environment and the levels of microorganisms associated with dental caries among the different types of brackets. MATERIAL AND

methodsTwenty patients received two self-ligating brackets: In-Ovation®R, SmartClipTM, and one conventional GeminiTM. Saliva was collected before bonding (S0), 30 (S1) and 60 (S2) days after bonding. One sample of each bracket was removed at 30 and 60 days for the in situ analysis. Checkerboard DNA-DNA Hybridization was employed to evaluate the levels of microbial species as-sociated with dental caries. Data were evaluated by nonparametric Friedman and Wilcoxon tests at 5% significance level.

resultsThe salivary levels of L. casei (p=0.033), S. sobrinus (p=0.011), and S. sanguinis (p=0.004) increased in S1. The in situ analyses showed alteration in S. mutans (p=0.047), whose highest levels were observed to the In-Ovation®R.

conclusionsThe orthodontic appliances break the salivary homeostasis of microorganisms involved in dental caries. The contamination pattern was different between self-ligating and conventional brackets. The In-Ovation®R presented worse performance considering the levels of cariogenic bacterial species.

Indexed as

AdolescentChildDental BondingDental CariesDNA ProbesFemaleHomeostasisHumansMaleOrthodontic Appliance DesignOrthodontic BracketsSalivaStatistics, NonparametricTime FactorsDNA Probes

Identifiers

PMID30994775
PMCPMC6459231
OpenAlexW2939617164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.