Evidence map›Paper›PMID 30994471›Full record

ArticleJMIR medical informatics2019

A Computer Application to Predict Adverse Events in the Short-Term Evolution of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease.

Inmaculada Arostegui, María José Legarreta, Irantzu Barrio, Cristobal Esteban, Susana Garcia-Gutierrez, Urko Aguirre, José María Quintana, IRYSS-COPD Group

2 registry-linked trialsAbstract read
In one paragraph

Article in JMIR medical informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00102401 nacompletednot on this map

Comparing the Effects of an Internet-Based to an Established Dyspnea Self-Management Program on Dyspnea, Exercise Behavior, and Pulmonary Exacerbations in Patients With COPD

TypeinterventionalSponsorRobert Wood Johnson FoundationRan2003 to 2007Enrolled50ConditionsChronic Obstructive Pulmonary DiseaseArmsInternet-based Dyspnea Self-Management Program, Face-to-face Dyspnea Self-Management Program
NCT02434536 completednot on this map

Assessment of the Appropriateness Admission From Emergency Departments in the Exacerbation of COPD. Validity of Explicit Criteria and Study of the Variability Between Different Centers of NHS. Multicenter Study IRYSS-Appropriateness-COPD.

Typeobservational_patient_registrySponsorHospital Galdakao-UsansoloRan2006 to 2010Enrolled2,487ConditionsCOPD
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Inmaculada ArosteguiDepartamento de Matemática Aplicada y Estadística e Investigación Operativa, The University of the Basque Country UPV/EHU, Leioa, Spain.ORCID 0000-0002-6848-2240
María José LegarretaDepartamento de Matemática Aplicada y Estadística e Investigación Operativa, The University of the Basque Country UPV/EHU, Leioa, Spain.ORCID 0000-0002-1778-5196
Irantzu BarrioDepartamento de Matemática Aplicada y Estadística e Investigación Operativa, The University of the Basque Country UPV/EHU, Leioa, Spain.ORCID 0000-0003-0648-5769
Cristobal EstebanRed de Investigación en Servicios Sanitarios en Enfermedades Crónicas, Galdakao, Spain.ORCID 0000-0001-9878-7806
Susana Garcia-GutierrezRed de Investigación en Servicios Sanitarios en Enfermedades Crónicas, Galdakao, Spain.ORCID 0000-0002-8474-2479
Urko AguirreRed de Investigación en Servicios Sanitarios en Enfermedades Crónicas, Galdakao, Spain.ORCID 0000-0002-8049-3030
José María QuintanaRed de Investigación en Servicios Sanitarios en Enfermedades Crónicas, Galdakao, Spain.ORCID 0000-0003-2170-7876
IRYSS-COPD Group *Red de Investigación en Servicios Sanitarios en Enfermedades Crónicas, Galdakao, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is a common chronic disease. Exacerbations of COPD (eCOPD) contribute to the worsening of the disease and the patient's evolution. There are some clinical prediction rules that may help to stratify patients with eCOPD by their risk of poor evolution or adverse events. The translation of these clinical prediction rules into computer applications would allow their implementation in clinical practice.

objectiveThe goal of this study was to create a computer application to predict various outcomes related to adverse events of short-term evolution in eCOPD patients attending an emergency department (ED) based on valid and reliable clinical prediction rules.

methodsA computer application, Prediction of Evolution of patients with eCOPD (PrEveCOPD), was created to predict 2 outcomes related to adverse events: (1) mortality during hospital admission or within a week after an ED visit and (2) admission to an intensive care unit (ICU) or an intermediate respiratory care unit (IRCU) during the eCOPD episode. The algorithms included in the computer tool were based on clinical prediction rules previously developed and validated within the Investigación en Resultados y Servicios de Salud COPD study. The app was developed for Windows and Android systems, using Visual Studio 2008 and Eclipse, respectively.

resultsThe PrEveCOPD computer application implements the prediction models previously developed and validated for 2 relevant adverse events in the short-term evolution of patients with eCOPD. The application runs under Windows and Android systems and it can be used locally or remotely as a Web application. Full description of the clinical prediction rules as well as the original references is included on the screen. Input of the predictive variables is controlled for out-of-range and missing values. Language can be switched between English and Spanish. The application is available for downloading and installing on a computer, as a mobile app, or to be used remotely via internet.

conclusionsThe PrEveCOPD app shows how clinical prediction rules can be summarized into simple and easy to use tools, which allow for the estimation of the risk of short-term mortality and ICU or IRCU admission for patients with eCOPD. The app can be used on any computer device, including mobile phones or tablets, and it can guide the clinicians to a valid stratification of patients attending the ED with eCOPD.

trial registrationClinicalTrials.gov NCT00102401; https://clinicaltrials.gov/ct2/show/results/NCT02434536 (Archived by WebCite at http://www.webcitation.org/76iwTxYuA). INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/1472-6963-11-322.

Indexed as

clinical prediction ruleCOPDdisease exacerbationintensive caremobile appmortality

Identifiers

PMID30994471
PMCPMC6492058

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.