Evidence map›Paper›PMID 30994181›Full record

ArticleCardiology journal2021

Poor long-term outcome in acute coronary syndrome in a real-life setting: Ten-year outcome of the TACOS study.

Kaari K Konttila, Kimmo Koivula, Markku J Eskola, Mika Martiskainen, Heini Huhtala, Vesa K Virtanen, Jussi Mikkelsson, Kati Järvelä, Kari O Niemelä, Pekka J Karhunen and 1 more

Abstract read
In one paragraph

Article in Cardiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kaari K KonttilaFaculty of Medicine and Health Technology, Tampere University, Tampere.
Kimmo KoivulaSouth-Karelia Central Hospital, Finland.
Markku J EskolaHeart Center, Tampere University Hospital, Finland.
Mika MartiskainenFaculty of Medicine and Health Technology, Tampere University, Tampere.
Heini HuhtalaFaculty of Social Sciences, Tampere University, Finland.
Vesa K VirtanenHeart Center, Tampere University Hospital, Finland.
Jussi MikkelssonHeart Center, Satakunta Central Hospital, Pori, Finland.
Kati JärveläHeart Center, Tampere University Hospital, Finland.
Kari O NiemeläHeart Center, Tampere University Hospital, Finland.
Pekka J KarhunenFaculty of Medicine and Health Technology, Tampere University and Fimlab Laboratories Tampere University Hospital, Tampere, Finland.
Kjell C NikusHeart Center, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, 33520 Tampere, Finland. kjell.nikus@sydansairaala.fi.ORCID 0000-0002-9345-9851

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term outcome of the three categories of acute coronary syndrome (ACS) in real-life patient cohorts is not well known. The objective of this study was to survey the 10-year outcome of an ACS patient cohort admitted to a university hospital and to explore factors affecting the outcome.

methodsA total of 1188 consecutive patients (median age 73 years) with ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI) or unstable angina pectoris (UA) in 2002-2003 were included and followed up for ≥ 10 years.

resultsMortality for STEMI, NSTEMI and UA patients during the follow-up period was 52.5%, 69.9% and 41.0% (p < 0.001), respectively. In multivariable Cox regression analysis, only age and creatinine level at admission were independently associated with patient outcome in all the three ACS categories when analyzed separately.

conclusionsAll the three ACS categories proved to have high mortality rates during long-term followup in a real-life patient cohort. NSTEMI patients had worse outcome than STEMI and UA patients during the whole follow-up period. Our study results indicate clear differences in the prognostic significance of various demographic and therapeutic parameters within the three ACS categories.

Indexed as

Acute Coronary SyndromeMyocardial InfarctionAgedAngina, UnstableHumansNon-ST Elevated Myocardial InfarctionST Elevation Myocardial InfarctionTreatment Outcomeacute coronary syndromemyocardial infarctionprognosisunstable angina

Identifiers

PMID30994181
PMCPMC8078956

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.