Evidence map›Paper›PMID 30994094›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Antibiotic Resistance in Enterobacteriaceae from Surface Waters in Urban Brazil Highlights the Risks of Poor Sanitation.

Patricia S Bartley, T Nicholas Domitrovic, Vanessa T Moretto, Cleiton S Santos, Rafael Ponce-Terashima, Mitermayer G Reis, Lucio M Barbosa, Ronald E Blanton, Robert A Bonomo, Federico Perez

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Structure of Bacterial Community with Resistance to Antibiotics in Aquatic Environments. A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Widespread Distribution of Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Review
  6. Improved diagnostic stewardship in carbapenem-resistantJournal of medical microbiology · 2025
    Article
  7. Review
  8. Detection and Characterization of Carbapenemase-ProducingAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Effects of EOs vs. Antibiotics onMolecules (Basel, Switzerland) · 2022
    Article
  13. Review
  14. The occurrence of antimicrobial residues and antimicrobial resistance genes in urban drinking water and sewage in Southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  15. Review
  16. Molecular Diagnostic Tools Applied for Assessing Microbial Water Quality.International journal of environmental research and public health · 2022
    Review
  17. Extended-Spectrum Beta-Lactamases ProducingInfection and drug resistance · 2022
    Review
  18. Article
  19. Review
  20. Genomic Analysis of Carbapenem-ResistantFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Patricia S BartleyDepartment of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
T Nicholas DomitrovicCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Vanessa T MorettoLaboratory Oswaldo Cruz Foundation, Salvador, Brazil.
Cleiton S SantosLaboratory Oswaldo Cruz Foundation, Salvador, Brazil.
Rafael Ponce-TerashimaDepartment of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.
Mitermayer G ReisDivision of Infectious Diseases, School of Medicine and Public Health, Bahiana University, Salvador, Brazil.
Lucio M BarbosaDivision of Infectious Diseases, School of Medicine and Public Health, Bahiana University, Salvador, Brazil.
Ronald E BlantonCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Robert A BonomoMedical Service and Geriatrics Research, Education and Clinical Center (GRECC), Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio.
Federico PerezCleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Case Western Reserve University, Cleveland, Ohio.
Fundação Oswaldo Cruz · BRCenter for Global Health · USCase Western Reserve University · USEscola Bahiana de Medicina e Saúde Pública · BRGeriatric Research Education and Clinical Center · USLouis Stokes Cleveland VA Medical Center · USUniversity Hospitals of Cleveland · US

Funding

Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
Environmental influences on urban schistosomiasis transmission and eliminationR01AI121330 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI BLANTON, RONALD E · 2017 to 2021
$2.3M
Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniaeR21AI114508 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., VAN DUIN, DAVID · 2015 to 2016
$445k
NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI100560NIAID NIH HHS R01 AI121330NIAID NIH HHS R21 AI114508
6 · The paper itself

Abstract

Surface waters are an unappreciated reservoir of antimicrobial resistance (AMR). Poor sanitation brings different species of environmental bacteria into contact, facilitating horizontal gene transfer. To investigate the role of surface waters as potential reservoirs of AMR, we studied the point prevalence of fecal contamination, AMR genes, and Enterobacteriaceae in an urban lake and rural river system in Northeast Brazil in comparison with a lake and sewer system in Northeast Ohio in the United States. Surface water samples were examined for evidence of human fecal contamination using microbial source tracking and screened for plasmid-mediated fluoroquinolone resistance and carbapenemase genes. Enterobacteriaceae were detected using selective agar followed by antimicrobial susceptibility testing and detection of AMR genes by microarray, and classified by repetitive sequence-based polymerase chain reaction and multilocus sequence typing. Concentrations of human fecal bacteria in the Brazilian urban lake and sewage in Northeast Ohio were similarly high. Filtered water samples from the Brazilian urban lake, however, showed the presence of

Indexed as

Water MicrobiologyAnti-Bacterial AgentsBacterial ProteinsBrazilDrug Resistance, Multiple, BacterialEnterobacteriaceaeGene Expression Regulation, BacterialHumansLakesSanitationUrban HealthAnti-Bacterial AgentsBacterial Proteins

Identifiers

PMID30994094
PMCPMC6553890
OpenAlexW2981200181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.