ArticleJournal of surgical oncology2019
Sarcomas of the mandible.
Article in Journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Sarcomatoid squamous cell carcinoma of the mandible: Radiologic-pathologic correlation and diagnostic pitfalls of an aggressive osteolytic lesion.Radiology case reports · 2026Article
- Undifferentiated High-Grade Pleomorphic Sarcoma of the Posterior Mandible: A Report of a Rare Case.Cureus · 2026Article
- Article
- Planning of physiotherapeutic procedure in patients after mandible reconstruction taking into account donor site: a literature review.European journal of medical research · 2023Review
- Clinical and imaging features of eight cases of Ewing sarcoma of the jaw.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2023Article
- Application of DMAIC Cycle and Modeling as Tools for Health Technology Assessment in a University Hospital.Journal of healthcare engineering · 2021Article
- Article
- The temporo-mandibular joint: Reconstruction of the condyle post-ablation.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
introductionSarcomas of the mandible are extremely rare tumors, with osteosarcoma being the most common, followed by Ewing's sarcoma MATERIALS AND
methodsA retrospective review of the clinical records, imaging studies, and pathology slides of patients with sarcoma of the mandible at a Tertiary Care Cancer Center from 1998 to 2014 was undertaken. The impact of neoadjuvant chemotherapy and postoperative radiotherapy with or without chemotherapy was studied, and factors impacting upon local control and disease-specific survival were analyzed.
resultsTwenty-two patients were treated over the study period, comprising of 15 males and seven females. External swelling, intraoral growth, or facial numbness were the presenting symptoms. Eighteen patients had osteosarcoma and four had the Ewing's sarcoma. Nine patients received neoadjuvant chemotherapy. All but one patient underwent surgery. Eleven had negative margins, with 90% recurrence-free survival at 3 years, compared to 10 with positive or close margins, leading to 67% recurrence-free survival. None of the patients receiving neoadjuvant chemotherapy developed recurrence and all were alive at 3 years. The impact of postoperative radiotherapy or adjuvant chemotherapy was not statistically significant.
conclusionsWide surgical resection with negative margins remains the hallmark of surgical treatment.
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