Evidence map›Paper›PMID 30993659›Full record

ReviewAging clinical and experimental research2019

Practical guidance for engaging patients in health research, treatment guidelines and regulatory processes: results of an expert group meeting organized by the World Health Organization (WHO) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).

Maarten de Wit, Cyrus Cooper, Peter Tugwell, Nathalie Bere, John Kirwan, Philip G Conaghan, Charlotte Roberts, Isabelle Aujoulat, Nasser Al-Daghri, Islene Araujo de Carvalho and 18 more

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05571124 (The Implementation of a Web-based Workplace Exercise Intervention in the Reduction of Spinal Pain in Sedentary Administrative Personnel), which is not on this map. Cited by 42 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05571124 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Implementation of a Web-based Workplace Exercise Intervention in the Reduction of Spinal Pain in Sedentary Administrative Personnel: Protocol of a Mixed Methodology Study.

TypeinterventionalSponsorUniversitat de LleidaRan2023 to 2024Enrolled66ConditionsBack Pain, Sedentary BehaviorArmsTherapeutic Exercise Intervention
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Evaluation of temporomandibular disorder self-management apps in Australia: a systematic review to inform clinical use.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2025
    Pooled it
  2. Pooled it
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  5. Trial
  6. [DNVF Memorandum Participatory Health Services Research (Part 1)].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2026
    Article
  7. Article
  8. Article
  9. Article
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  12. Review
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  14. Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  15. Review
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  19. Article
  20. Patients' experience with a community pharmacy fall prevention service.Exploratory research in clinical and social pharmacy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Maarten de WitDepartment of Medical Humanities, Amsterdam University Medical Centre, Amsterdam, The Netherlands.
Cyrus CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
Peter TugwellDepartment of Medicine, University of Ottawa, Ottawa, Canada.
Nathalie BerePublic Engagement Department, European Medicines Agency, 30 Churchill Place, Canary Wharf, London, E14 5EU, UK.
John KirwanEmeritus Professor of Rheumatic Diseases, University of Bristol, Bristol, UK.
Philip G ConaghanLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.
Charlotte RobertsInternational Consortium for Health Outcomes Measurement, Hamilton House, 4 Mabledon Place, Bloomsbury, London, WC1H 9BB, UK.
Isabelle AujoulatUniversité Catholique de Louvain, Institute of Health & Society, Brussels, Belgium.
Nasser Al-DaghriChair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Islene Araujo de CarvalhoDepartment of Ageing and Life Course, World Health Organization, 20 Avenue Appia, 1211, Geneva 27, Switzerland.
Mary BarkerMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
Nicola BedlingtonEuropean Patients' Forum, Chaussée d'Etterbeek 180, Etterbeek, 1040, Brussels, Belgium.
Maria Luisa BrandiDepartment of Surgery and Translational Medicine, University of Florence, Florence, Italy.
Olivier BruyèreWHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium.
Nansa BurletWHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium.
Philippe HalboutInternational Osteoporosis Foundation, 9 Rue Juste-Olivier, 1260, Nyon, Switzerland.
Mickaël HiligsmannDepartment of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
Famida JiwaOsteoporosis Canada, Toronto, ON, Canada.
John A KanisMary McKillop Health Institute, Australian Catholic University, Melbourne, Australia.
Andrea LaslopScientific Office, Federal Office for Safety in Health Care, Austrian Agency for Health and Food Safety, Vienna, Austria.
Wendy LawrenceMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK.
Daniel PintoDepartment of Physical Therapy, College of Health Sciences, Marquette University, Milwaukee, USA.
Concepción Prieto YerroSpanish Agency for Drugs and Medical Devices, Calle Campezo 1, Building 8, 28022, Madrid, Spain.
Véronique RabendaDepartment of Public Health, Epidemiology and Health Economics, University of Liège, CHU Sart Tilman B23, 4000, Liège, Belgium.
René RizzoliWHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium.
Marieke Scholte-VoshaarDepartment of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.
Mila VlaskovskaMedical Faculty, Department of Pharmacology, Medical University Sofia, 2, Zdrave Str, 1431, Sofia, Bulgaria.
Jean-Yves ReginsterWHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium. jyreginster@uliege.be.ORCID http://orcid.org/0000-0001-6290-752X

Funding

Medical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/4
6 · The paper itself

Abstract

There is increasing emphasis on patient-centred research to support the development, approval and reimbursement of health interventions that best meet patients' needs. However, there is currently little guidance on how meaningful patient engagement may be achieved. An expert working group, representing a wide range of stakeholders and disciplines, was convened by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the World Health Organization (WHO). Through a structured, collaborative process the group generated practical guidance to facilitate optimal patient engagement in clinical development and regulatory decisions. Patient engagement is a relational process. The principles outlined in this report were based on lessons learned through applied experience and on an extensive dialogue among the expert participants. This practice guidance forms a starting point from which tailoring of the approach to suit different chronic diseases may be undertaken.

Indexed as

OsteoarthritisOsteoporosisPatient ParticipationConsensusHealth Services ResearchHumansPractice Guidelines as TopicSocieties, MedicalWorld Health OrganizationOutcomes researchPatient engagementPatient preferenceRegulatory processTreatment guidelines

Identifiers

PMID30993659
PMCPMC6589151

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.