Evidence map›Paper›PMID 30993640›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

Structure Elucidation of Macrolide Antibiotics Using MS

Andrew R Johnson, Erin E Carlson

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Andrew R JohnsonDepartment of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN, 47405, USA.
Erin E CarlsonDepartment of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN, 47405, USA. carlsone@umn.edu.ORCID http://orcid.org/0000-0001-8287-8893
Indiana University Bloomington · USUniversity of Minnesota · US

Funding

Alfred P. Sloan Foundation noneDirectorate for Mathematical and Physical Sciences 1518379
6 · The paper itself

Abstract

The 14- and 16-membered macrolide antibiotics are an important structural class. Ubiquitously produced by a number of bacterial strains, namely actinomycetes, purification and structure elucidation of the wide array of analogs is challenging, both for discovery efforts and methodologies to monitor for byproducts, metabolites, and contaminants. Collision-induced dissociation mass spectrometry offers an attractive solution, enabling characterization of mixtures, and providing a wealth of structural information. However, interpretation of these spectra can be difficult. We present a study of 14- and 16-membered macrolide antibiotics, including MS

Indexed as

Anti-Bacterial AgentsDeuteriumErythromycinJosamycinLeucomycinsMacrolidesOleandomycinSpectrometry, Mass, Electrospray IonizationSpiramycinTylosinWaterAnti-Bacterial AgentsDeuteriumErythromycinJosamycinLeucomycinsMacrolidesOleandomycinSpiramycinTylosinWaterMacrolide antibiotics, Multilevel fragmentation, Structure elucidation

Identifiers

PMID30993640
OpenAlexW2940441997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.