Evidence map›Paper›PMID 30993502›Full record

ArticleJournal of autism and developmental disorders2019

The Importance of Temperament for Understanding Early Manifestations of Autism Spectrum Disorder in High-Risk Infants.

Sarah J Paterson, Jason J Wolff, Jed T Elison, Breanna Winder-Patel, Lonnie Zwaigenbaum, Annette Estes, Juhi Pandey, Robert T Schultz, Kelly Botteron, Stephen R Dager and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Identification of Early Temperament Profiles in Infants at Elevated Likelihood for Autism and Attention-Deficit/Hyperactivity Disorder.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  4. Review
  5. Infant sleep predicts trajectories of social attention and later autism traits.Journal of child psychology and psychiatry, and allied disciplines · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Attend Less, Fear More: Elevated Distress to Social Threat in Toddlers With Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sarah J PatersonDepartment of Psychology, Temple University, Philadelphia, PA, USA. sjpaterson@mac.com.
Jason J WolffDepartment of Educational Psychology, University of Minnesota, Minneapolis, MN, USA.
Jed T ElisonInstitute of Child Development & Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Breanna Winder-PatelThe MIND Institute, UC Davis, Sacramento, CA, USA.
Lonnie ZwaigenbaumDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Annette EstesDepartment of Speech and Hearing Sciences, University of Washington, Seattle, WA, USA.
Juhi PandeyCenter for Autism Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Robert T SchultzCenter for Autism Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Kelly BotteronDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO, USA.
Stephen R DagerDepartment of Radiology, University of Washington, Seattle, WA, USA.
Heather C HazlettThe Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Joseph PivenThe Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
IBIS Network

Funding

Brain Imaging Markers of Response to Intervention in Toddlers with AutismK01MH101653 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOLFF, JASON J · 2013 to 2017
$651k
NIH HHS HD055741-S1NIH HHS R01-HD055741NIMH NIH HHS K01-MH101653
6 · The paper itself

Abstract

The present study investigated the relationship between infant temperament characteristics and autism spectrum disorder (ASD) risk status. Temperament was examined at 6, 12, and 24 months in 282 infants at high familial risk for ASD and 114 low-risk controls using the Infant Behavior Questionnaire-Revised and Early Childhood Behavior Questionnaire. Infants were divided into three groups at 24 months: High-Risk Positive-classified as ASD (HR Pos), High-Risk Negative (HR Neg), and Low-Risk Negative (LR Neg). At 6 and 12 months HR Pos infants exhibited lower Surgency and Regulatory Capacity than LR Neg infants. By 12 months they also demonstrated increased Negative Affect. Group differences remained, when early signs of ASD were controlled for, suggesting that temperament differences could be useful targets for understanding the development of ASD.

Indexed as

TemperamentAutism Spectrum DisorderChildChild, PreschoolFemaleHumansInfantInfant BehaviorMaleRisk FactorsAutism spectrum disorderInfancyTemperament

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.