Evidence map›Paper›PMID 30993161›Full record

ArticleGynecologic oncology reports2019

A case of incidental endometrial adenocarcinoma diagnosed in early pregnancy and managed conservatively.

I Rizzuto, R Nicholson, K Dickinson, H J Juang, W MacNab, B Rufford

Open access · goldAbstract readCase Reports
In one paragraph

Article in Gynecologic oncology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

I RizzutoDepartment of Gynaecological Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich hospital, Suffolk, United Kingdom.
R NicholsonDepartment of Gynaecological Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich hospital, Suffolk, United Kingdom.
K DickinsonDepartment of Histopathology, Ipswich Hospital, Suffolk, United Kingdom.
H J JuangDepartment of Gynaecological Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich hospital, Suffolk, United Kingdom.
W MacNabDepartment of Gynaecological Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich hospital, Suffolk, United Kingdom.
B RuffordDepartment of Gynaecological Oncology, East Suffolk and North Essex NHS Foundation Trust, Ipswich hospital, Suffolk, United Kingdom.
East Suffolk and North Essex NHS Foundation Trust · GBIpswich Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 29-year old nulliparous woman diagnosed with a grade 1 endometrioid adenocarcinoma of the endometrium arising from an atypical polypoid adenomyoma, while being investigated for a suspected threatened miscarriage at 7 weeks gestation. She presented complaining of vaginal bleeding and a small amount of soft tissue in the cervical os was found and sent for histology. An ultrasound scan was performed, which confirmed an intrauterine ongoing pregnancy. The patient had no further episodes of unscheduled bleeding. After the confirmed histological diagnosis an MRI scan was requested, and there were no evidence of myometrial invasion or distant metastasis. The patient was seen at each trimester, remained asymptomatic throughout the pregnancy and had a normal delivery at term. There was no evidence of any residual endometrioid adenocarcinoma in the post-delivery specimen. Six weeks post-natally an endometrial biopsy was performed, which was normal. She is still in remission over a period of 8 years follow-up. Endometrial adenocarcinoma in young pregnant women is a rare clinical circumstance. This case shows that conservative management in young women is possible including in a case of an incidental diagnosis in pregnancy.

Indexed as

Endometrial cancerFertility sparing-surgeryHormonal treatment

Identifiers

PMID30993161
PMCPMC6449706
OpenAlexW2923058885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.