Evidence map›Paper›PMID 30993092›Full record

ArticleJournal of cancer prevention2019

Interaction Effect Between Breast Density and Reproductive Factors on Breast Cancer Risk in Korean Population.

Se-Eun Lim, HyoJin Ahn, Eun Sook Lee, Sun-Young Kong, So-Youn Jung, Seeyoun Lee, Han-Sung Kang, Eun-Gyeong Lee, Jai Hong Han, Boyoung Park

Open access · diamondAbstract read
In one paragraph

Article in Journal of cancer prevention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The epidemiologic factors associated with breast density: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Se-Eun LimDepartment of Medicine, Hanyang University College of Medicine, Seoul, Korea.
HyoJin AhnDepartment of Medicine, Hanyang University College of Medicine, Seoul, Korea.
Eun Sook LeeResearch Institute, National Cancer Center, Goyang, Korea.
Sun-Young KongResearch Institute, National Cancer Center, Goyang, Korea.
So-Youn JungResearch Institute, National Cancer Center, Goyang, Korea.
Seeyoun LeeResearch Institute, National Cancer Center, Goyang, Korea.
Han-Sung KangResearch Institute, National Cancer Center, Goyang, Korea.
Eun-Gyeong LeeNational Cancer Center Hospital, Goyang, Korea.
Jai Hong HanNational Cancer Center Hospital, Goyang, Korea.
Boyoung ParkDepartment of Medicine, Hanyang University College of Medicine, Seoul, Korea.
National Cancer Center · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was conducted to explore the effect of known risk factors, focusing on risk factors including age at menarche, age at menopause, number of children, family history of breast cancer, and age at first birth according to breast density, in consideration of interaction among East-Asian women.

methodsCase-control study with 2,123 cases and 2,121 controls with mammographic density was conducted. Using the mammographic film, breast density was measured using Breast Imaging-Reporting and Data System. To identify the association of selected reproductive factors including age at menarche, age at menopause, number of children, family history of breast cancer, and age at first birth according to breast density, stratified analysis was conducted according to breast density groups and interaction effects was assessed. The results were presented with adjusted OR and 95% CIs.

resultsSignificant interaction effect between age at first birth and breast density on breast cancer (

conclusionsAge at first birth showed significant interaction with breast density on breast cancer risk. Further studies considering biologically plausable model between exposure, intermediate outcomes and breast cancer risk with prospective design need to be undertaken in East Asian women.

Indexed as

Breast densityBreast neoplasmsReproductive history

Identifiers

PMID30993092
PMCPMC6453588
OpenAlexW2926940619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.