ArticleGut pathogens2019
Diagnosing and tracing the pathogens of infantile infectious diarrhea by amplicon sequencing.
Article in Gut pathogens, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Metagenomic identification of disease-causingMicrobial genomics · 2025Article
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- A 6-year retrospective study of clinical features, microbiology, and genomics of Shiga toxin-producingMicrobiology spectrum · 2024Article
- Effects of dietary protein level on small intestinal morphology, occludin protein, and bacterial diversity in weaned piglets.Food science & nutrition · 2022Article
- The relationship between the gut microbiome and the risk of respiratory infections among newborns.Communications medicine · 2022Article
- Article
- Using next-generation sequencing to develop a Shigella species threshold and profile faecal samples from suspected diarrhoea cases.Folia microbiologica · 2021Article
- Study on parental satisfaction and clinical treatment outcomes of 128 diarrheic children receiving comprehensive nursing.American journal of translational research · 2021Article
- Childhood diarrhoeal diseases in developing countries.Heliyon · 2020Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetagenomic methods have been widely applied to study the relationship between gut microbiota and human health. To test whether metagenomic amplicon sequencing could be an effective method to diagnose and trace the pathogens of infantile infectious diarrhea, the fecal samples of 20 diarrheic and 13 healthy infants were collected. After 16S rDNA amplicon sequencing, diversity analyses were carried out. The relationship between the pathogens of the gut microbiota and geography of patients was analyzed.
resultsThe diversity of the gut microbiota in diarrheic infants was significantly lower than that of the gut microbiota in healthy ones and that, the composition of gut microbiota in the diarrheic group was significantly different than that of the gut microbiota in the healthy group. The results also indicated that in some of the patients, the amounts of
conclusionsThe method of using high-throughput DNA sequencing and a comprehensive and deep data analysis can be a new strategy to detect and trace pathogens in infantile infectious diarrhea.
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