ReviewJournal of pain research2019
The impact of multisite pain on functional outcomes in older adults: biopsychosocial considerations.
Review in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of multimorbid degenerative lumbar spinal stenosis with knee or hip osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2022Pooled it
- Effectivenss of electroacupuncture for skeletal muscle pain in Parkinson's disease: a Clinical randomized controlled trial.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Trial
- Prevalence and Associated Factors of Depressive Symptoms Among Persons Aged 45 Years and Older in Indonesia in 2023: Overall and Sex-Specific Analyses.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Biobehavioral pain profiling of minoritized adults with chronic widespread pain and clinical obesity before and after bariatric surgery: study protocol for a longitudinal, observational cohort study.medRxiv : the preprint server for health sciences · 2026Article
- Ecological momentary pain and physical activity volume and patterns in older adults with chronic multisite pain.BMC geriatrics · 2026Observational
- Number of pain points and multisite pain in people 80 years and older in Thailand.Pain reports · 2026Article
- Bi-directional associations between alcohol consumption and pain among non-manual workers: a random-intercept cross-lagged panel analysis in the British Whitehall II cohort study.Alcohol and alcoholism (Oxford, Oxfordshire) · 2026Article
- Beyond pain presence: the impact of multisite pain and pain interference on cognitive functioning among middle-aged and older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Comparisons and associations of psychological factors and the number of painful sites in wheelchair basketball athletes with and without shoulder pain: A cross-sectional case-control study.The journal of spinal cord medicine · 2025Article
- Association between pain expansion, physical activity, strength, motor problems and frailty risk in middle-aged and older European people: A cross-sectional study.Aging clinical and experimental research · 2025Article
- Clinical Benefits of Ibuprofen Arginine: A Narrative Review.Pain and therapy · 2025Review
- Pain patterns and their association with psychological measures among people accessing an online pain management program.Pain management · 2025Article
- Association of loneliness with the risk of pain in older Chinese adults.Scientific reports · 2025Article
- Changes in Widespread Pain After Surgical Weight Loss in Racialized Adults: A Secondary Analysis From a 2-Year Longitudinal Study.The journal of pain · 2024Article
- Unlocking the Potential of the Elderly Population in Serbia: A Modeling Study on Musculoskeletal Disorders and Associated Factors.Journal of clinical medicine · 2024Article
- Multisite Musculoskeletal Pain Is Associated with Long-Term Declined Physical Quality of Life and Knee-Related Quality of Life in Older Adults with or at Risk of Knee Osteoarthritis.Medicina (Kaunas, Lithuania) · 2024Article
- Physical therapy interventions for people experiencing homelessness to improve pain and self-perceived health status.BMC public health · 2024Article
- Considerations beyond spine pain: do different co-occurring lower body joint pains differentially influence physical function and quality of life ratings?BMC musculoskeletal disorders · 2024Article
- Article
- Frequency of multisite non-hand joint involvement in patients with thumb-base osteoarthritis, and associations with functional and patient-reported outcomes.Osteoarthritis and cartilage open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Multisite pain, or pain that occurs simultaneously at >1 anatomical site, is more prevalent than single-site pain. While multisite pain affects over half of older adults, it remains an understudied pain entity that may have important functional implications in an aging population. Greater understanding of this complex pain entity from a biopsychosocial perspective is critical for optimizing clinical and functional outcomes in older adults with pain. Therefore, the primary purpose of this review is to summarize the relationship between multisite pain and functional outcomes in older adults to further elucidate the impact of multisite pain as a distinct entity within this population. A comprehensive literature search revealed 17 peer-reviewed articles. Multisite pain in older individuals is associated with reductions in several physical function domains: 1) lower-extremity mobility; 2) upper-extremity impairments; 3) balance and increased fall risk; and 4) general disability and poor physical function. Further, multisite pain in older individuals is associated with psychological dysfunction (eg, anxiety and depressive symptoms) and social factors (eg, income and education). Overall, this review highlights the scant literature investigating the functional implications of multisite pain in an aging population. Further, while multisite pain appears to have functional consequences, the neurobiological mechanisms contributing to this relationship are unknown. Thus, how this pain characteristic may contribute to the variability in pain-related functional outcomes among older adults is not clear. Future investigations are strongly warranted to advance the understanding of multisite pain and its broad impact on physical and psychosocial function in older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.