Evidence map›Paper›PMID 30992633›Full record

ArticleBulletin of the World Health Organization2019

Implementing prevention policies for mother-to-child transmission of HIV in rural Malawi, South Africa and United Republic of Tanzania, 2013-2016.

Harriet Jones, Alison Wringe, Jim Todd, John Songo, Francesc Xavier Gómez-Olivé, Mosa Moshabela, Eveline Geubbels, Mukome Nyamhagatta, Thoko Kalua, Mark Urassa and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Bulletin of the World Health Organization, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  13. The Intergenerational Impact of a Slow Pandemic: HIV and Children.New directions for child and adolescent development · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Harriet JonesDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
Alison WringeDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
Jim ToddDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
John SongoMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Francesc Xavier Gómez-OlivéMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, University of the Witwatersrand, South Africa.
Mosa MoshabelaSchool of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Eveline GeubbelsDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
Mukome NyamhagattaMinistry of Health, Community Development, Gender, Elderly and Children, Dodoma, United Republic of Tanzania.
Thoko KaluaMinistry of Health, Lilongwe, Malawi.
Mark UrassaNational Institute of Medical Research, Mwanza, Tanzania.
Basia ZabaDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.
Jenny RenjuDepartment of Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England.

Funding

Medical Research Council MR/P014313/1Wellcome Trust
6 · The paper itself

Abstract

objectiveTo assess adoption of World Health Organization (WHO) guidance into national policies for prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) and to monitor implementation of guidelines at facility level in rural Malawi, South Africa and the United Republic of Tanzania.

methodsWe summarized national PMTCT policies and WHO guidance for 15 indicators across the cascades of maternal and infant care over 2013-2016. Two survey rounds were conducted (2013-2015 and 2015-2016) in 46 health facilities serving five health and demographic surveillance system populations. We administered structured questionnaires to facility managers to describe service delivery. We report the proportions of facilities implementing each indicator and the frequency and durations of stock-outs of supplies, by site and survey round.

findingsIn all countries, national policies influencing the maternal and infant PMTCT cascade of care aligned with WHO guidelines by 2016; most inter-country policy variations concerned linkage to routine HIV care. The proportion of facilities delivering post-test counselling, same-day antiretroviral therapy (ART) initiation, antenatal care and ART provision in the same building, and Option B+ increased or remained at 100% in all sites. Progress in implementing policies on infant diagnosis and treatment varied across sites. Stock-outs of HIV test kits or antiretroviral drugs in the past year declined overall, but were reported by at least one facility per site in both rounds.

conclusionProgress has been made in implementing PMTCT policy in these settings. However, persistent gaps across the infant cascade of care and supply-chain challenges, risk undermining infant HIV elimination goals.

Indexed as

World Health OrganizationAfrica South of the SaharaAnti-Retroviral AgentsCounselingFemaleGlobal HealthGuidelines as TopicHIV InfectionsHumansInfantInfant CareInfant, NewbornInfectious Disease Transmission, VerticalPrenatal CarePublic Health SurveillanceSocioeconomic FactorsAnti-Retroviral Agents

Identifiers

PMID30992633
PMCPMC6453322

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.