Evidence map›Paper›PMID 30992541›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Dronedarone induces regression of coronary artery remodeling related to better global antioxidant status.

Begoña Quintana-Villamandos, Laia Pazó-Sayós, Silvia Magdalena Arribas, Pilar Rodríguez-Rodríguez, Rainer H Böger, Nicole Lüneburg, Emilio Delgado-Baeza, Maria Carmen González

Abstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Effect of dronedarone vs. placebo on atrial fibrillation progression: a post hoc analysis from ATHENA trial.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Trial
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Begoña Quintana-VillamandosDepartment of Anesthesiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain. begoquinti@gmail.com.
Laia Pazó-SayósDepartment of Anesthesiology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Silvia Magdalena ArribasDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Pilar Rodríguez-RodríguezDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Rainer H BögerDepartment of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nicole LüneburgDepartment of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Emilio Delgado-BaezaMolecular Biology Laboratory, Department of Experimental Medicine and Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Maria Carmen GonzálezDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ESUniversidad Autónoma de Madrid · ESUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our group previously demonstrated that dronedarone induces regression of left ventricular hypertrophy in spontaneously hypertensive rats (SHRs). We assessed changes in vascular remodeling and oxidative stress following short-term use of this agent. The coronary artery was isolated from 10-month-old male SHRs treated with 100 mg kg

Indexed as

AnimalsAntioxidantsArginineCoronary VesselsDronedaroneMaleNitric OxideRatsRats, Inbred SHRRats, Inbred WKYVascular RemodelingVasoconstrictionAntioxidantsArginineDronedaroneNitric OxideN,N-dimethylarginineAsymmetric dimethylarginineCoronary artery remodelingDronedaroneOXY-SCORESpontaneously hypertensive rat

Identifiers

PMID30992541
OpenAlexW2938548665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.