Evidence map›Paper›PMID 30992394›Full record

ArticleBioscience reports2019

MiR-205 suppresses epithelial-mesenchymal transition and inhibits tumor growth of human glioma through down-regulation of HOXD9.

Bin Dai, Guanghua Zhou, Zhiqiang Hu, Guangtong Zhu, Beibei Mao, Haiyang Su, Qingbin Jia

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bin DaiDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, No.10 Tieyi Rd, Yangfangdian, Haidian District, Beijing, 100038, P.R. China.
Guanghua ZhouDepartment of Neurosurgery, Liaocheng People's Hospital of Shandong, No.67 Dongchang West Road, Liaocheng, Shandong Province, 252000, P.R. China.
Zhiqiang HuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, No.10 Tieyi Rd, Yangfangdian, Haidian District, Beijing, 100038, P.R. China.
Guangtong ZhuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, No.10 Tieyi Rd, Yangfangdian, Haidian District, Beijing, 100038, P.R. China.
Beibei MaoDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, No.10 Tieyi Rd, Yangfangdian, Haidian District, Beijing, 100038, P.R. China.
Haiyang SuDepartment of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, No.10 Tieyi Rd, Yangfangdian, Haidian District, Beijing, 100038, P.R. China.
Qingbin JiaDepartment of Neurosurgery, Liaocheng People's Hospital of Shandong, No.67 Dongchang West Road, Liaocheng, Shandong Province, 252000, P.R. China dfmoh72@163.com.ORCID 0000-0002-3690-6600
Capital Medical University · CNLiaocheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) plays a pivotal role in cancer progression. Hsa-miR-205 is considered one of the fundamental regulators of EMT. In the present study, we found that miR-205 was down-regulated in glioma tissues and human glioma cells U87 and U251. Meanwhile, miR-205 overexpression enhanced E-cadherin, reduced mesenchymal markers, and decreased cell proliferation, migration, and invasion

Indexed as

AnimalsBrain NeoplasmsCadherinsCell Line, TumorCell MovementCell ProliferationDown-RegulationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticGliomaHomeodomain ProteinsHumansMaleMiceMice, Inbred NODMice, SCIDCadherinsHomeodomain ProteinsHOXD9 protein, humanMicroRNAsMIR205, humanNeoplasm ProteinsEpithelial-mesenchymal transitionGliomaHOXD9miR-205tumor

Identifiers

PMID30992394
PMCPMC6522733
OpenAlexW2938810613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.