Evidence map›Paper›PMID 30992392›Full record

ArticleBioscience reports2019

MPSSS impairs the immunosuppressive function of cancer-associated fibroblasts via the TLR4-NF-κB pathway.

Yuwei Xu, Jing Ma, Qilin Zheng, Yuanyuan Wang, Minghua Hu, Fangli Ma, Zhihai Qin, Ningjing Lei, Ning Tao

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuwei XuMedical Research Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China.ORCID 0000-0002-6477-2857
Jing MaSchool of Basic Medical Sciences of Southwest Medical University, Luzhou 646000, China.ORCID 0000-0001-8882-5186
Qilin ZhengKey Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yuanyuan WangInfinitus Chinese Herbal Immunity Research Centre, Infinitus Company Ltd, Guangzhou 510635, China.ORCID 0000-0002-7596-7406
Minghua HuInfinitus Chinese Herbal Immunity Research Centre, Infinitus Company Ltd, Guangzhou 510635, China.ORCID 0000-0002-1389-7369
Fangli MaInfinitus Chinese Herbal Immunity Research Centre, Infinitus Company Ltd, Guangzhou 510635, China.ORCID 0000-0002-3243-3973
Zhihai QinMedical Research Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China zhihai@ibp.ac.cn lnj717@zzu.edu.cn tao@ibp.ac.cn.ORCID 0000-0001-9793-7964
Ningjing LeiMedical Research Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450052, China zhihai@ibp.ac.cn lnj717@zzu.edu.cn tao@ibp.ac.cn.ORCID 0000-0002-8615-4056
Ning TaoKey Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China zhihai@ibp.ac.cn lnj717@zzu.edu.cn tao@ibp.ac.cn.ORCID 0000-0002-0021-4995
Chinese Academy of Sciences · CNInfinitus (China) · CNFirst Affiliated Hospital of Zhengzhou University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polysaccharides MPSSS was extracted from

Indexed as

Gene Expression Regulation, NeoplasticAnimalsAntineoplastic AgentsCancer-Associated FibroblastsCell Line, TumorCell ProliferationCoculture TechniquesFungal PolysaccharidesHumansMaleMiceMice, Inbred BALB CMyeloid Differentiation Factor 88NF-kappa BProstatic NeoplasmsShiitake MushroomsAntineoplastic AgentsFungal PolysaccharidesMYD88 protein, humanMyeloid Differentiation Factor 88NF-kappa BTLR4 protein, humanToll-Like Receptor 4antitumor immunitycancer-associated fibroblastsimmunosuppressionLentinus edodes polysaccharidesprostate cancer

Identifiers

PMID30992392
PMCPMC6509060
OpenAlexW2937707565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.