Evidence map›Paper›PMID 30992390›Full record

ArticleBioscience reports2019

miR-26a prevents neural stem cells from apoptosis via β-catenin signaling pathway in cardiac arrest-induced brain damage.

Fang Li, Hongyan Wei, Hengjie Li, Xin Li, Chunlin Hu, Jie Zhang, Yubin Deng, Xiaoxing Liao

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fang LiDepartment of Emergency, the Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650101, China.
Hongyan WeiDepartment of Emergency, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
Hengjie LiDepartment of Emergency, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
Xin LiDepartment of Emergency, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
Chunlin HuDepartment of Emergency, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
Jie ZhangThe Second Department of Hepatobiliary Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650032, China.
Yubin DengTranslational Medicine Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China nhfxg97@163.com jxrfia2@163.com.
Xiaoxing LiaoDepartment of Emergency, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China nhfxg97@163.com jxrfia2@163.com.ORCID 0000-0001-7198-2505
Sun Yat-sen University · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural stem cells (NSCs) transplantation is one of the most promising strategies for the treatment of CA-induced brain damage. The transplanted NSCs could differentiate into new neuron and replace the damaged one. However, the poor survival of NSCs in severe hypoxic condition is the limiting step to make the best use of this kind of therapy. In the present study, we investigated whether the overexpression of miR-26a improves the survival of NSCs in hypoxic environment

Indexed as

AnimalsApoptosisbeta CateninCell HypoxiaCells, CulturedDown-RegulationFemaleHeart ArrestHypoxia, BrainMaleMicroRNAsNeural Stem CellsRats, Sprague-DawleyUp-RegulationWnt Signaling Pathwaybeta CateninMicroRNAsMIRN26 microRNA, ratGSK-3βmiR-26aNSCs and CAβ-catenin

Identifiers

PMID30992390
PMCPMC6522814
OpenAlexW2940305335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.