Evidence map›Paper›PMID 30992312›Full record

ArticleMolecular & cellular proteomics : MCP2019

Loss of BAP1 Results in Growth Inhibition and Enhances Mesenchymal-Epithelial Transition in Kidney Tumor Cells.

Pengsheng Chen, Huan Wang, Wenhao Zhang, Yuling Chen, Yang Lv, Di Wu, Mingzhou Guo, Haiteng Deng

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

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  18. Genomics and Functional Genomics of Malignant Pleural Mesothelioma.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Pengsheng ChenFrom the ‡MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systematic Biology, School of Life Sciences.
Huan Wang§MOE Key Laboratory for Protein Science, School of Life Sciences, Tsinghua University, Beijing, China.
Wenhao ZhangFrom the ‡MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systematic Biology, School of Life Sciences.
Yuling ChenFrom the ‡MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systematic Biology, School of Life Sciences;; ¶Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, China.
Yang Lv‖Department of Gastroenterology and Hepatology, and Center of Nephrology, Chinese PLA General Hospital, Beijing, China.
Di Wu‖Department of Gastroenterology and Hepatology, and Center of Nephrology, Chinese PLA General Hospital, Beijing, China.
Mingzhou Guo‖Department of Gastroenterology and Hepatology, and Center of Nephrology, Chinese PLA General Hospital, Beijing, China.
Haiteng DengFrom the ‡MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systematic Biology, School of Life Sciences;. Electronic address: dht@tsinghua.edu.cn.
Chinese PLA General Hospital · CNKing Center · USPeking University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRCA1-associated protein 1 (BAP1) is a member of the ubiquitin C-terminal hydrolase family of deubiquitinating enzymes and is implicated in transcriptional regulation. The

Indexed as

Epithelial-Mesenchymal TransitionCell Line, TumorCell ProliferationDown-RegulationGene Expression Regulation, NeoplasticGene OntologyHumansKidney NeoplasmsProteomeProteomicsSnail Family Transcription FactorsStress FibersSurvival AnalysisTumor Suppressor ProteinsUbiquitinationUbiquitin ThiolesteraseBAP1 protein, humanProteomeSnail Family Transcription FactorsTumor Suppressor ProteinsUbiquitin ThiolesteraseBAP1Cell Adhesion*Clear Cell Renal Cell CarcinomaDeubiquitinasesKidney CancerMesenchymal–Epithelial TransitionOmicsProteomicsSnailTandem Mass Spectrometry

Identifiers

PMID30992312
PMCPMC6601205
OpenAlexW2935960355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.