Evidence map›Paper›PMID 30992126›Full record

ReviewBiochimica et biophysica acta. Molecular cell research2018

Calcium signaling and the lytic cycle of the Apicomplexan parasite Toxoplasma gondii.

Miryam Andrea Hortua Triana, Karla M Márquez-Nogueras, Stephen A Vella, Silvia N J Moreno

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta. Molecular cell research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functional analysis of CaParasitology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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  11. Article
  12. Article
  13. Article
  14. Melatonin as a Circadian Marker forInternational journal of molecular sciences · 2024
    Review
  15. Article
  16. Apigeninidin chloride disruptsFrontiers in cellular and infection microbiology · 2024
    Article
  17. Proteomics Applications inPathogens (Basel, Switzerland) · 2023
    Review
  18. Article
  19. Animal venoms: a novel source of anti-Frontiers in pharmacology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Miryam Andrea Hortua TrianaCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
Karla M Márquez-NoguerasCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
Stephen A VellaCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
Silvia N J MorenoCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA; Department of Cellular Biology, University of Georgia, Athens, GA 30602, USA. Electronic address: smoreno@uga.edu.
University of Georgia · US

Funding

Training in Tropical and Emerging Global Diseases - SupplementT32AI060546 · NIAID · UNIVERSITY OF GEORGIA (UGA) · PI Silvia N Moreno, Vasant Muralidharan · 2004 to 2026
$5.1M
The Toxoplasma apicoplast and calcium signalingR01AI128356 · NIAID · UNIVERSITY OF GEORGIA · PI MORENO, SILVIA N · 2017 to 2021
$2.0M
The plant-like vacuole of Toxoplasma gondiiR01AI096836 · NIAID · UNIVERSITY OF GEORGIA · PI MORENO, SILVIA N · 2012 to 2016
$1.8M
NIAID NIH HHS R01 AI096836NIAID NIH HHS R01 AI128356NIAID NIH HHS T32 AI060546
6 · The paper itself

Abstract

Toxoplasma gondii has a complex life cycle involving different hosts and is dependent on fast responses, as the parasite reacts to changing environmental conditions. T. gondii causes disease by lysing the host cells that it infects and it does this by reiterating its lytic cycle, which consists of host cell invasion, replication inside the host cell, and egress causing host cell lysis. Calcium ion (Ca

Indexed as

Calcium SignalingCalciumCalcium-Binding ProteinsDisease SusceptibilityFocal Adhesion Kinase 2Life Cycle StagesProtozoan ProteinsToxoplasmaToxoplasmosisCalciumCalcium-Binding ProteinsFocal Adhesion Kinase 2Protozoan ProteinsCalcium binding proteinsCalcium dependent protein kinasesCalcium signalingLytic cyclePathogenicityToxoplasma gondii

Identifiers

PMID30992126
PMCPMC6477927
OpenAlexW2886056927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.