Evidence map›Paper›PMID 30992070›Full record

ReviewWorld journal of surgical oncology2019

Grade III meningioma with gastro-intestinal tract and brain metastases: case report and review of the literature.

Laura Bender, Benoit Lhermitte, Hélène Carinato, Seyyid Baloglu, Mehdi Helali, Hélène Cebula, Delphine Antoni, Georges Noel

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in World journal of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Malignant Meningiomas: From Diagnostics to Treatment.Diagnostics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Laura BenderRadiotherapy Department, Centre Paul Strauss, UNICANCER, 3, rue de la Porte de l'hôpital, F-67065, Strasbourg, France. laura_2708@hotmail.fr.ORCID http://orcid.org/0000-0003-3486-8505
Benoit LhermittePathology Service, University Hospital Hautepierre, 1, rue Molière, 67000, Strasbourg, France.
Hélène CarinatoMedical Oncology Department, Centre Paul Strauss, UNICANCER, 3, rue de la Porte de l'hôpital, F-67065, Strasbourg, France.
Seyyid BalogluRadiology Department, University Hospital Hautepierre, 1, rue Molière, 67000, Strasbourg, France.
Mehdi HelaliNuclear Medecine Department, Centre Paul Strauss, UNICANCER, 3, rue de la Porte de l'hôpital, F-67065, Strasbourg, France.
Hélène CebulaNeurosurgery Department, University Hospital Hautepierre, 1, rue Molière, 67000, Strasbourg, France.
Delphine AntoniRadiotherapy Department, Centre Paul Strauss, UNICANCER, 3, rue de la Porte de l'hôpital, F-67065, Strasbourg, France.
Georges NoelRadiotherapy Department, Centre Paul Strauss, UNICANCER, 3, rue de la Porte de l'hôpital, F-67065, Strasbourg, France.
Hôpital d'Hautepierre · FRCentre National de la Recherche Scientifique · FRLevi Strauss (United States) · USHôpital Civil, Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeningioma is the most common adult primary intracranial tumor. Malignant meningioma is a rare variant of meningioma. The prognosis for the patients with these tumors is poor, due to the tumor's capacity for relapse and to develop distant metastases. These tumors can present the same evolutionary course as aggressive carcinoma. CASE DESCRIPTION: We report the case of distant brain and gastro-intestinal tract (GIT) metastases. A 78-year-old patient developed malignant meningioma with a Ki-67 proliferative index of 40%. According to guidelines, surgery followed by postoperative radiotherapy (RT) was performed. Three months after the end of RT, he presented histologically proven meningioma distant brain and GIT metastases.

conclusionsTo our knowledge, this is the first case of meningioma GIT metastases. Also, we report the difficulty to confirm the diagnosis of meningioma metastases. Indeed, malignant meningioma has the same histopathological features as melanoma or carcinoma. The standard of care for the management of malignant meningioma is gross total surgery followed by postoperative radiotherapy. Metastatic meningioma is uncommon and no guidelines for the management of recurrent or metastatic meningioma have yet been published. However, several studies reported systemic therapeutic options such as antibody against VEGF, somatostatin analogs, PDGF-R, and VEGF-R tyrosine kinase inhibitors, in the case of recurrent or metastatic meningioma. We also made a review of the actual literature of systemic treatment options for metastatic meningioma.

Indexed as

AgedBrain NeoplasmsGastrointestinal NeoplasmsHumansMaleMeningeal NeoplasmsMeningiomaNeoplasm GradingBevacizumabBrain metastasesGastro-intestinal tract metastasesMalignant meningiomaSystemic treatment

Identifiers

PMID30992070
PMCPMC6469106
OpenAlexW2945388933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.