Evidence map›Paper›PMID 30992038›Full record

ArticleTrials2019

The effectiveness of high intensity intermittent training on metabolic, reproductive and mental health in women with polycystic ovary syndrome: study protocol for the iHIT- randomised controlled trial.

Danielle Hiam, Rhiannon Patten, Melanie Gibson-Helm, Alba Moreno-Asso, Luke McIlvenna, Itamar Levinger, Cheryce Harrison, Lisa J Moran, Anju Joham, Alex Parker and 3 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Danielle HiamInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Rhiannon PattenInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Melanie Gibson-HelmMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Alba Moreno-AssoInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Luke McIlvennaInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Itamar LevingerInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Cheryce HarrisonMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Lisa J MoranMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Anju JohamMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Alex ParkerInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia.
Soulmaz ShorakaeMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
David SimarMechanisms of Disease and Translational Research, School of Medical Sciences, UNSW Sydney, Sydney, Australia.
Nigel SteptoInstitute for Health and Sport, Victoria University, PO Box 14428, Melbourne, Victoria, 8001, Australia. nigel.stepto@vu.edu.au.ORCID http://orcid.org/0000-0002-0875-6836
Monash University · AUVictoria University · AUMonash Health · AUThe University of Melbourne · AUUNSW Sydney · AU

Funding

Centre of Research Excellence in PCOS APP1078444
6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is a reproductive-metabolic condition. Insulin resistance is a hallmark of PCOS and is related to increased hyperandrogenism that drives inherent metabolic, reproductive and psychological features of the syndrome. Insulin resistance in women with PCOS is managed by weight loss, lifestyle interventions (i.e. exercise, diet) and insulin-sensitising medications. This manuscript describes the protocol of our study evaluating the effectiveness of high intensity intermittent training (HIIT) or moderate intensity exercise on cardiometabolic, reproductive and mental health in overweight women with PCOS. METHODS/

designWe will employ a three arm, parallel-group, randomised controlled trial recruiting 60 women diagnosed with PCOS, aged between 18 and 45 years and with a body mass index (BMI) greater than 25 kg/m DISCUSSION: This trial aims to demonstrate the comparative efficacy and maintenance of different exercise intensities to advance the understanding of PCOS management and provide insight into the optimal exercise intensity for improved cardiometabolic outcomes. Secondary outcomes will include the impact of different exercise protocols on reproductive hormone profiles, mental health and health-related quality of life.

trial registrationAustralian New Zealand Clinical Trials Registry, ACTRN12615000242527 . Registered on 17 March 2015.

Indexed as

Mental HealthRandomized Controlled Trials as TopicReproductive HealthAdolescentAdultExercise TherapyFemaleHumansInsulin ResistanceMiddle AgedOutcome Assessment, Health CarePolycystic Ovary SyndromeQuality of LifeSample SizeYoung AdultCardiometabolic healthCardiorespiratory fitnessExerciseExercise therapyHigh-intensity interval trainingInsulinMental healthOverweightPolycystic ovary syndrome

Identifiers

PMID30992038
PMCPMC6469064
OpenAlexW2945820156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.