Evidence map›Paper›PMID 30991908›Full record

Trial reportPsychiatric services (Washington, D.C.)2019

Outcomes of Psychoeducation and a Text Messaging Adherence Intervention Among Individuals With Hypertension and Bipolar Disorder.

Jennifer B Levin, Martha Sajatovic, Mahboob Rahman, Michelle E Aebi, Curt Tatsuoka, Colin Depp, Clint Cushman, Elaine Johnston, Kristin A Cassidy, Carol Blixen and 4 more

Abstract readClinical Trial
In one paragraph

Trial report in Psychiatric services (Washington, D.C.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Investigating the Role of Situational Disruptors in Engagement with Digital Mental Health Tools.CSCW : proceedings of the Conference on Computer-Supported Cooperative Work. Conference on Computer-Supported Cooperative Work · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Investigating the Role of Context in the Delivery of Text Messages for Supporting Psychological Wellbeing.Proceedings of the SIGCHI conference on human factors in computing systems. CHI Conference · 2023
    Article
  9. Proceedings of the ACM on human-computer interaction · 2022
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jennifer B LevinDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Martha SajatovicDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Mahboob RahmanDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Michelle E AebiDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Curt TatsuokaDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Colin DeppDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Clint CushmanDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Elaine JohnstonDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Kristin A CassidyDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Carol BlixenDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Logan EskewDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Peter J KleinDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
Edna Fuentes-CasianoDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).
David J MooreDepartment of Psychiatry, Case Western Reserve University School of Medicine, Cleveland (Levin, Sajatovic, Rahman, Aebi, Cassidy, Blixen, Klein, Fuentes-Casiano); Neurological and Behavioral Outcomes Center (Levin, Sajatovic, Tatsuoka, Blixen) and Department of Medicine (Rahman), University Hospitals Cleveland Medical Center, Cleveland; Department of Psychiatry, University of California, San Diego, La Jolla (Depp, Cushman, Johnston, Moore); Department of Psychology, Cleveland State University, Cleveland (Eskew).

Funding

Transforming Translational Science and Education to Benefit Human HealthUL1TR000043 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY · 2012 to 2015
$26.8M
Improving Medication Adherence in Hypertensive Individuals with Bipolar DisorderR21HL132364 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LEVIN, JENNIFER BETH · 2016 to 2017
$449k
NCATS NIH HHS UL1 TR000043NHLBI NIH HHS R21 HL132364
6 · The paper itself

Abstract

objectiveThis study evaluated the feasibility, acceptability, and preliminary efficacy of psychoeducation plus an automated text messaging intervention (Individualized Texting for Adherence Building-Cardiovascular [iTAB-CV]) to improve adherence to antihypertensives and bipolar disorder medication.

methodsAfter a psychoeducation program, iTAB-CV was administered for 2 months. In month 1, participants received one educational-motivational and one mood rating text daily. In month 2, medication reminders were added.

resultsThe sample (N=38) was 74% African American and 53% women, with a mean±SD age of 51.53±9.06. Antihypertensive nonadherence decreased from a mean of 43%±23% to 21%±18% at 12 weeks (χ

conclusionsIn this uncontrolled trial, participants were highly engaged and medication adherence and reduced systolic blood pressure were sustained after psychoeducation plus iTAB-CV. Because iTAB-CV is automated and delivered remotely, it has the potential to reach a large and challenging population.

Indexed as

Medication AdherenceOutcome and Process Assessment, Health CarePatient Education as TopicPsychotherapyReminder SystemsText MessagingAdultBipolar DisorderFeasibility StudiesFemaleHumansHypertensionMaleMiddle AgedPatient Acceptance of Health Carebipolar disorderhypertensionmedication adherencem-Healthtext messaging

Identifiers

PMID30991908
PMCPMC6602799

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.