Evidence map›Paper›PMID 30991836›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Undifferentiated spermatogonia regulate

Parag A Parekh, Thomas X Garcia, Reham Waheeb, Vivek Jain, Pooja Gandhi, Marvin L Meistrich, Gunapala Shetty, Marie-Claude Hofmann

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Exploring dysregulated miRNAs in cryptorchidism: a systematic review.The Journal of international medical research · 2021
    Pooled it
  2. Review
  3. Article
  4. Meta-GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Retinoid metabolism: new insights.Journal of molecular endocrinology · 2022
    Review
  12. Identification and Expression Pattern ofAnimals : an open access journal from MDPI · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Parag A ParekhDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Thomas X GarciaDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Reham WaheebDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Vivek JainDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Pooja GandhiDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Marvin L MeistrichDepartment of Experimental Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Gunapala ShettyDepartment of Experimental Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
Marie-Claude HofmannDepartment of Endocrine Neoplasia and Hormonal Disorders, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USAlexandria University · EGUniversity of Houston - Clear Lake · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Research Training Program in Toxicology and Environmental HealthT32ES007326 · NIEHS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Jodi A. Flaws · 2000 to 2026
$8.7M
Molecular Regulation of the Perinatal Male Germ Cell NicheR01HD081244 · NICHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOFMANN, MARIE-CLAUDE CATHERINE · 2014 to 2018
$1.6M
FUNCTIONAL GENOMICS AND PROTEOMICS TO REVEAL REPRODUCTIVE-TRACT SPECIFIC PROTEINSR01HD095341 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI GARCIA, THOMAS · 2018 to 2020
$1.2M
NCI NIH HHS P30 CA016672NICHD NIH HHS R01 HD081244NICHD NIH HHS R01 HD095341NIEHS NIH HHS T32 ES007326
6 · The paper itself

Abstract

Cytochrome P450 family 26 subfamily B member 1 (CYP26B1) regulates the concentration of all-trans retinoic acid (RA) and plays a key role in germ cell differentiation by controlling local distribution of RA. The mechanisms regulating

Indexed as

Cell DifferentiationGene Expression Regulation, DevelopmentalSignal TransductionAnimalsCell Cycle ProteinsJagged-1 ProteinMaleMiceMice, TransgenicPromoter Regions, GeneticReceptors, NotchRetinoic Acid 4-HydroxylaseSOX9 Transcription FactorSpermatogoniaSteroidogenic Factor 1Cell Cycle ProteinsCyp26b1 protein, mouseHey1 protein, mouseJag1 protein, mouseJagged-1 ProteinReceptors, NotchRetinoic Acid 4-HydroxylaseSOX9 protein, humanSOX9 Transcription FactorSteroidogenic Factor 1steroidogenic factor 1, mouseJAG1Sertoli cellspermatogenesis

Identifiers

PMID30991836
PMCPMC6593872
OpenAlexW2936752872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.