Evidence map›Paper›PMID 30991738›Full record

ArticleCancers2019

Identification of KIF11 As a Novel Target in Meningioma.

Gerhard Jungwirth, Tao Yu, Mahmoud Moustafa, Carmen Rapp, Rolf Warta, Christine Jungk, Felix Sahm, Steffen Dettling, Klaus Zweckberger, Katrin Lamszus and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Kinesin Spindle Protein (KIF11) in Mitosis and Cancer.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Research progress of kinesin family in neurological diseases.Frontiers in cellular neuroscience · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. KIF11 Is a Promising Therapeutic Target for Thyroid Cancer Treatment.Computational and mathematical methods in medicine · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 2 countries.

Gerhard JungwirthDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. gerhard.jungwirth@med.uni-heidelberg.de.
Tao YuDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. tao.yu@med.uni-heidelberg.de.
Mahmoud MoustafaDepartment of Radiation Oncology, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. Mahmoud.Moustafa@med.uni-heidelberg.de.
Carmen RappDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. carmen.rapp@med.uni-heidelberg.de.
Rolf WartaDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. rolf.warta@med.uni-heidelberg.de.
Christine JungkDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. christine.jungk@med.uni-heidelberg.de.
Felix SahmDepartment of Neuropathology, Institute of Pathology, University of Heidelberg, German Cancer Consortium, CCU Neuropathology, German Cancer Research Center, INF 224, D-69120 Heidelberg, Germany. Felix.Sahm@med.uni-heidelberg.de.
Steffen DettlingDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. steffen.dettling@gmail.com.
Klaus ZweckbergerDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. klaus.zweckberger@med.uni-heidelberg.de.
Katrin LamszusDepartment of Neurosurgery, University Medical Center Hamburg Eppendorf, Martinistr 52, D-20246 Hamburg, Germany. lamszus@uke.uni-hamburg.de.
Christian SenftDepartment of Neurosurgery, University Hospital, Goethe University, Schleusenweg 2, D-60528 Frankfurt am Main, Germany. c.senft@med.uni-frankfurt.de.
Mario LoehrDepartment of Neurosurgery, University Hospital Wuerzburg, Josef-Schneider-Str 2, D-97080 Wuerzburg, Germany. loehr_m1@ukw.de.
Almuth F KeßlerDepartment of Neurosurgery, University Hospital Wuerzburg, Josef-Schneider-Str 2, D-97080 Wuerzburg, Germany. kessler_a1@ukw.de.
Ralf KetterDepartment of Neurosurgery, Saarland University, Medical School, Kirrberger Str, D-66421 Homburg, Germany. Ralf.Ketter@uks.eu.
Manfred WestphalDepartment of Neurosurgery, University Medical Center Hamburg Eppendorf, Martinistr 52, D-20246 Hamburg, Germany. westphal@uke.de.
Juergen DebusDepartment of Radiation Oncology, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. Juergen.Debus@med.uni-heidelberg.de.
Andreas von DeimlingDepartment of Neuropathology, Institute of Pathology, University of Heidelberg, German Cancer Consortium, CCU Neuropathology, German Cancer Research Center, INF 224, D-69120 Heidelberg, Germany. Andreas.vonDeimling@med.uni-heidelberg.de.
Matthias SimonDepartment of Neurosurgery, Bethel Clinic, Burgsteig 13, D-33617 Bielefeld, Germany. matthias.simon@evkb.de.
Andreas UnterbergDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. andreas.unterberg@med.uni-heidelberg.de.
Amir AbdollahiDepartment of Radiation Oncology, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. Amir.Abdollahi@med.uni-heidelberg.de.
Christel Herold-MendeDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, INF 400, D-69120 Heidelberg, Germany. H.Mende@med.uni-heidelberg.de.
Heidelberg University · DEGerman Cancer Research Center · DEUniversität Hamburg · DEUniversitätsklinikum Würzburg · DEEvangelisches Krankenhaus Bielefeld · DEGoethe University Frankfurt · DESaarland University · DESuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinesins play an important role in many physiological functions including intracellular vesicle transport and mitosis. The emerging role of kinesins in different cancers led us to investigate the expression and functional role of kinesins in meningioma. Therefore, we re-analyzed our previous microarray dataset of benign, atypical, and anaplastic meningiomas (

Indexed as

KIFKIF11kinesinmeningiomaNCH93

Identifiers

PMID30991738
PMCPMC6521001
OpenAlexW2936346124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.