Evidence map›Paper›PMID 30991717›Full record

ArticleInternational journal of molecular sciences2019

The Polyphenol-Rich Extract from

Elodie Clain, Juliano G Haddad, Andrea C Koishi, Laura Sinigaglia, Walid Rachidi, Philippe Desprès, Claudia N Duarte Dos Santos, Pascale Guiraud, Nolwenn Jouvenet, Chaker El Kalamouni

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. The Antiviral Activity of Polyphenols.Molecular nutrition & food research · 2025
    Review
  2. Anti-DENV-2 Activity of Ethanolic Extracts fromPlants (Basel, Switzerland) · 2024
    Article
  3. Review
  4. Role of phytocompounds as the potential anti-viral agent: an overview.Naunyn-Schmiedeberg's archives of pharmacology · 2023
    Review
  5. Review
  6. Antiviral Effect ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
  7. Zika virus as an emerging arbovirus of international public health concern.Osong public health and research perspectives · 2022
    Article
  8. Natural products as Zika antivirals.Medicinal research reviews · 2022
    Review
  9. Review
  10. Aqueous Extract ofAntioxidants (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Review
  13. Molecules (Basel, Switzerland) · 2021
    Article
  14. Cranberry (Pathogens (Basel, Switzerland) · 2021
    Article
  15. Review
  16. Review
  17. Flavonoids as Molecules With Anti-Frontiers in microbiology · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elodie ClainUniversité de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249, Unité Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, Sainte Clotilde, 97490 La Réunion, France. marie-elodie.clain@univ-reunion.fr.
Juliano G HaddadUniversité de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249, Unité Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, Sainte Clotilde, 97490 La Réunion, France. juliano.haddad@univ-reunion.fr.
Andrea C KoishiLaboratorio de Virologia Molecular, Instituto Carlos Chagas, ICC/FIOCRUZ/PR, Curitiba, Parana 81350-010, Brazil. ackoishi@gmail.co.
Laura SinigagliaViral Genomics and Vaccination Unit, UMR CNRS 3569, Institut Pasteur, 75724 Paris, France. laura.sinigagli@gmail.com.
Walid RachidiUniversité Grenoble Alpes, SYMMES/CIBEST UMR 5819 UGA-CNRS-CEA, INAC/CEA, 38000 Grenoble, France. Walid.rachidi@univ-grenoble-alpes.fr.
Philippe DesprèsUniversité de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249, Unité Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, Sainte Clotilde, 97490 La Réunion, France. ackoishi@gmail.co.
Claudia N Duarte Dos SantosLaboratorio de Virologia Molecular, Instituto Carlos Chagas, ICC/FIOCRUZ/PR, Curitiba, Parana 81350-010, Brazil. clsantos@fiocruz.br.
Pascale GuiraudUniversité de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249, Unité Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, Sainte Clotilde, 97490 La Réunion, France. pascale.guiraud@univ-reunion.fr.
Nolwenn JouvenetViral Genomics and Vaccination Unit, UMR CNRS 3569, Institut Pasteur, 75724 Paris, France. nolwenn.jouvenet@pasteur.fr.
Chaker El KalamouniUniversité de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249, Unité Mixte Processus Infectieux en Milieu Insulaire Tropical, Plateforme Technologique CYROI, Sainte Clotilde, 97490 La Réunion, France. chaker.el-kalamouni@univ-reunion.fr.

Funding

CAPES-COFECUB Me889/17 ZIKANETConseil Régional de La Réunion ZIKAlert program, N° SYNERGIE: RE00001902INSERM-Transfert project: n°R16029FSResearch Federation BioST, Université de La Réunion ZIKAPAMIRE
6 · The paper itself

Abstract

The recent emergence and re-emergence of viral infections transmitted by vectors, such as the Zika virus (ZIKV) and Dengue virus (DENV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas of the world. Despite the high morbidity and mortality associated with these viral infections, antiviral therapies are missing. Medicinal plants have been widely used to treat various infectious diseases since millenaries. Several compounds extracted from plants exhibit potent effects against viruses in vitro, calling for further investigations regarding their efficacy as antiviral drugs. Here, we demonstrate that an extract from

Indexed as

AnimalsAntiviral AgentsCells, CulturedChlorocebus aethiopsDengueDengue VirusHumansMagnoliopsidaPlant ExtractsPlants, MedicinalPolyphenolsReunionVero CellsZika VirusZika Virus InfectionAntiviral AgentsPlant ExtractsPolyphenolsantiviral activityDengue virusnatural compoundsnutraceuticalsPsiloxylon mauritianumZika virus

Identifiers

PMID30991717
PMCPMC6515236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.