Evidence map›Paper›PMID 30991710›Full record

ArticleNutrients2019

Protective Effects of Moderate Ca Supplementation against Cd-Induced Bone Damage under Different Population-Relevant Doses in Young Female Rats.

Xiao Huang, Teng Liu, Meng Zhao, Haowei Fu, Jinming Wang, Qian Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiao HuangKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. huangxiao1998@163.com.
Teng LiuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. liu_teng6016@126.com.
Meng ZhaoKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. zhaomengmail@163.com.
Haowei FuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. 220183495@seu.edu.cn.
Jinming WangKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. u20130608@163.com.
Qian XuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 210009 Nanjing, China. q_xu68@163.com.
Southeast University · CN

Funding

Social Development Research Program of Jiangsu Province Science and Technology department BE2015646the National Natural Science Foundation of China 81673171
6 · The paper itself

Abstract

Estimation of the skeleton-protective effects of Ca in Cd-induced bone damage is helpful in the assessment of Cd health risk. The aim of this study was to identify whether Ca supplementation during exposure to different population-relevant doses of Cd can prevent Cd-induced bone damage under the tolerable upper intake level of Ca supplementation. Young female Sprague-Dawley rats were given different population-relevant doses of Cd (1, 5, and 50 mg Cd/kg diet) and Ca supplementation (0.4% Ca supplementation) intervention. Ca supplementation significantly decreased Cd-induced bone microstructure damage, increased bone biomechanics (

Indexed as

Dietary SupplementsAnimalsBiomarkersBone and BonesBone DensityBone DiseasesCadmiumCalciumDietEnvironmental ExposureFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseKidneyKlotho ProteinsBiomarkersCadmiumCalciumFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseKlotho Proteinsbonecadmiumcalciumfibroblast growth factor 23klotho

Identifiers

PMID30991710
PMCPMC6521033
OpenAlexW2937430488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.