ArticleNutrients2019
Low Zinc, Copper, and Manganese Intake is Associated with Depression and Anxiety Symptoms in the Japanese Working Population: Findings from the Eating Habit and Well-Being Study.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Associations of Dietary Copper, Selenium, and Manganese Intake With Depression: A Meta-Analysis of Observational Studies.Frontiers in nutrition · 2022Pooled it
- Investigating the effect of zinc supplementation on probability of relapse and mental health in patients with opioid use disorder undergoing methadone maintenance treatment.Substance abuse treatment, prevention, and policy · 2023Trial
- The role of zinc homeostasis in major depressive disorder: heterogeneous pathological mechanisms and therapeutic implications.Annals of medicine · 2026Review
- Iron deficiency and depression: evidence of critical risk periods.Frontiers in psychiatry · 2026Article
- Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.Food science & nutrition · 2025Article
- Plant-Derived Nutraceuticals in Mental Health and Brain Function: Mechanisms of Action and Therapeutic Potential.International journal of molecular sciences · 2025Review
- The association between fodmaps intake and psychological disorders in a large sample of Iranian adults.Scientific reports · 2025Article
- Changes in the distribution of elements in the liver and various brain regions in suicides from southeastern Poland.Scientific reports · 2025Article
- A prospective study of a whole blood metal mixture and depressive symptoms among Black women from Detroit, Michigan.Neurotoxicology · 2025Article
- Food Intake and Mental Health Among Middle School Students in Shandong Province: A Network Analysis.Psychology research and behavior management · 2025Article
- Associations of multiple trace elements with bipolar disorder in adolescents: A case-control study.PloS one · 2025Article
- Kashin-Beck Disease: A Risk Factor for Sarcopenia and Its Interaction with Selenium.Nutrients · 2024Article
- Psychiatric Symptoms in Wilson's Disease-Consequence ofInternational journal of molecular sciences · 2024Review
- Article
- Genetic Causal Associations between Various Serum Minerals and Risk of Depression: A Mendelian Randomization Study.Actas espanolas de psiquiatria · 2024Article
- Systematic Review and Meta-analysis of the Association Between Malnutrition and Risk of Depression in the Elderly.Alpha psychiatry · 2024Review
- Association between drinking water quality and mental health and the modifying role of diet: a prospective cohort study.BMC medicine · 2024Article
- Amelioration of nonylphenol-induced anxiety/depression-like behaviors in male rats using green tea and Zn-Se tea interventions.Toxicology research · 2024Article
- Dietary Factors Associated with Depressive Symptoms in Midlife Women 40-50 Years of Age Living in the United States.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Association between copper and Achilles tendon disease: a two-sample Mendelian randomization study.Frontiers in nutrition · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Epidemiological studies have suggested that there is an association between diet and mental health. The aim of this study was to investigate the association between the intake of six minerals and mental disorders in a cross-sectional study. We used data from the Eating Habit and Well-being study in Japanese workers. Kessler's six-item psychological distress scale was used to detect mental disorders, with a cut-off score of 12/13, and a validated food frequency questionnaire was used to estimate dietary mineral intake. A total of 2089 participants with no history of depression were included. The prevalence of mental disorders was 6.9%. The lowest quartiles of zinc, copper, and manganese intakes were associated with mental disorders, whereas the lowest quartiles of calcium, magnesium, and iron intake were not associated with mental disorders. Combination analysis of high (≥median) or low (<median) intake of zinc, copper, and manganese showed that low zinc and low copper intake, even with low or high manganese intake (odds ratio (OR), 2.71, 95% confidence interval (CI), 1.29-5.73, and OR, 3.06, 95% CI, 1.41-6.61, respectively) showed a higher OR than that of high zinc, high copper, and high manganese intake. Further studies are required to investigate the impact of dietary mineral intake on mental health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.