ArticleNeuroImage. Clinical2019
Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum.
Article in NeuroImage. Clinical, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Trial
- Sex differences in central insulin action: Effect of intranasal insulin on neural food cue reactivity in adults with normal weight and overweight.International journal of obesity (2005) · 2022Trial
- Harnessing food cue evoked neuroimaging towards treatment optimisation for obesity and binge eating disorder.Reviews in endocrine & metabolic disorders · 2026Review
- Attentional biases in self-control are associated with reward cue-related brain activity.Social cognitive and affective neuroscience · 2026Article
- A personalized approach to understanding food cravings and intake: a study protocol.Journal of eating disorders · 2025Article
- The Interplay Between Psychological and Neurobiological Predictors of Weight Regain: A Narrative Review.Nutrients · 2025Review
- What Is Food Noise? A Conceptual Model of Food Cue Reactivity.Nutrients · 2023Review
- Affective Response During Real-World Physical Activity as an Intervention Mediator.Exercise and sport sciences reviews · 2023Article
- Current Insights into the Potential Role of fMRI in Discovering the Mechanisms Underlying Obesity.Journal of clinical medicine · 2023Review
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- The effect of hunger state on hypothalamic functional connectivity in response to food cues.Human brain mapping · 2023Article
- The effects of an 8-week mindful eating intervention on anticipatory reward responses in striatum and midbrain.Frontiers in nutrition · 2023Article
- Dynamical alterations of brain function and gut microbiome in weight loss.Frontiers in cellular and infection microbiology · 2023Article
- Intermittent energy restriction changes the regional homogeneity of the obese human brain.Frontiers in neuroscience · 2023Article
- Habituation or sensitization of brain response to food cues: Temporal dynamic analysis in an functional magnetic resonance imaging study.Frontiers in human neuroscience · 2023Article
- Spatiotemporal profile of altered neural reactivity to food images in obesity: Reward system is altered automatically and predicts efficacy of weight loss intervention.Frontiers in neuroscience · 2023Article
- The influence of the subcortex and brain stem on overeating: How advances in functional neuroimaging can be applied to expand neurobiological models to beyond the cortex.Reviews in endocrine & metabolic disorders · 2022Review
- Computational approaches to predicting treatment response to obesity using neuroimaging.Reviews in endocrine & metabolic disorders · 2022Review
- Contrasting dorsal caudate functional connectivity patterns between frontal and temporal cortex with BMI increase: link to cognitive flexibility.International journal of obesity (2005) · 2021Article
- Brain Responses to High-Calorie Visual Food Cues in Individuals with Normal-Weight or Obesity: An Activation Likelihood Estimation Meta-Analysis.Brain sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased fMRI food cue reactivity in obesity, i.e. higher responses to high- vs. low-calorie food images, is a promising marker of the dysregulated brain reward system underlying enhanced susceptibility to obesogenic environmental cues. Recently, it has also been shown that weight loss interventions might affect fMRI food cue reactivity and that there is a close association between the alteration of cue reactivity and the outcome of the intervention. Here we tested whether fMRI food cue reactivity could be used as a marker of diet-induced early changes of neural processing in the striatum that are predictive of the outcome of the weight loss intervention. To this end we investigated the relationship between food cue reactivity in the striatum measured one month after the onset of the weight loss program and weight changes obtained at the end of the six-month intervention. We observed a significant correlation between BMI change measured after six months and early alterations of fMRI food cue reactivity in the striatum, including the bilateral putamen, right pallidum, and left caudate. Our findings provide evidence for diet-induced early alterations of fMRI food cue reactivity in the striatum that can predict the outcome of the weight loss intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.