Evidence map›Paper›PMID 30991023›Full record

ArticleCancer cell2019

The Yin and Yang of RNA Methylation: An Imbalance of Erasers Enhances Sensitivity to FTO Demethylase Small-Molecule Targeting in Leukemia Stem Cells.

Inge Van Der Werf, Catriona Jamieson

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cancer cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. The Key Role of RNA Modification in Breast Cancer.Frontiers in cell and developmental biology · 2022
    Review
  6. Review
  7. RNA NClinical and translational medicine · 2021
    Review
  8. Review
  9. Article
  10. RNA mInnovation (Cambridge (Mass.)) · 2020
    Review
  11. Epitranscriptomics in Normal and Malignant Hematopoiesis.International journal of molecular sciences · 2020
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Inge Van Der WerfDivision of Regenerative Medicine, Department of Medicine, Moores Cancer Center and Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA.
Catriona JamiesonDivision of Regenerative Medicine, Department of Medicine, Moores Cancer Center and Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA. Electronic address: cjamieson@ucsd.edu.
University of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A prevalent eukaryotic N

Indexed as

OncogenesAlpha-Ketoglutarate-Dependent Dioxygenase FTOHumansLeukemia, Myeloid, AcuteMethylationRNAStem CellsAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanRNA

Identifiers

PMID30991023
OpenAlexW2937441886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.