ArticlePloS one2019
Glyphosate, but not its metabolite AMPA, alters the honeybee gut microbiota.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 146 citations in OpenAlex.
- A network-based meta-analysis of the honeybee gut microbiome: geographic, seasonal, and pesticide-associated shifts.Scientific reports · 2026Pooled it
- Beneath the surface: non-target effects of multiple pesticides on the soil microbiome in organic and conventional agricultural European fields.Environmental science and pollution research international · 2026Article
- Article
- Fitness related effects of titanium dioxide nanoparticles and glyphosate exposure on Cardiocondyla obscurior.Environmental science and pollution research international · 2026Article
- Young honey bees Apis mellifera learn to avoid pollen contaminated with glyphosate or imidacloprid.Scientific reports · 2026Article
- Toxicological concerns regarding glyphosate, its formulations, and co-formulants as environmental pollutants: a review of published studies from 2010 to 2025.Archives of toxicology · 2025Review
- Glyphosate-Based Herbicides and Their Potential Impact on the Microbiota of Social Bees.Toxics · 2025Review
- Changes in bumblebee queen gut microbiotas during and after overwintering diapause.Insect molecular biology · 2025Article
- Article
- Glyphosate effects on growth and biofilm formation in bee gut symbionts and diverse associated bacteria.Applied and environmental microbiology · 2024Article
- The honeybee microbiota and its impact on health and disease.Nature reviews. Microbiology · 2024Review
- Phytochemicals, Probiotics, Recombinant Proteins: Enzymatic Remedies to Pesticide Poisonings in Bees.Environmental science & technology · 2024Review
- Lactic acid bacteria modulate the CncC pathway to enhance resistance to β-cypermethrin in the oriental fruit fly.The ISME journal · 2024Article
- Impact of glyphosate (RoundupGut microbes · 2023Review
- Gastrointestinal Microbial Ecology of Weaned Piglets Fed Diets with Different Levels of Glyphosate.Microbiology spectrum · 2023Article
- Pesticide exposure and the microbiota-gut-brain axis.The ISME journal · 2023Review
- Glyphosate and a glyphosate-based herbicide affect bumblebee gut microbiota.FEMS microbiology ecology · 2023Article
- No impacts of glyphosate or Crithidia bombi, or their combination, on the bumblebee microbiome.Scientific reports · 2023Article
- The effects of glyphosate, pure or in herbicide formulation, on bumble bees and their gut microbial communities.The Science of the total environment · 2023Article
- Impact of a Microbial Pest Control Product Containing Bacillus thuringiensis on Brood Development and Gut Microbiota of Apis mellifera Worker Honey Bees.Microbial ecology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The honeybee (Apis mellifera) has to cope with multiple environmental stressors, especially pesticides. Among those, the herbicide glyphosate and its main metabolite, the aminomethylphosphonic acid (AMPA), are among the most abundant and ubiquitous contaminant in the environment. Through the foraging and storing of contaminated resources, honeybees are exposed to these xenobiotics. As ingested glyphosate and AMPA are directly in contact with the honeybee gut microbiota, we used quantitative PCR to test whether they could induce significant changes in the relative abundance of the major gut bacterial taxa. Glyphosate induced a strong decrease in Snodgrassella alvi, a partial decrease of a Gilliamella apicola and an increase in Lactobacillus spp. abundances. In vitro, glyphosate reduced the growth of S. alvi and G. apicola but not Lactobacillus kunkeei. Although being no bee killer, we confirmed that glyphosate can have sublethal effects on the honeybee microbiota. To test whether such imbalanced microbiota could favor pathogen development, honeybees were exposed to glyphosate and to spores of the intestinal parasite Nosema ceranae. Glyphosate did not significantly enhance the effect of the parasite infection. Concerning AMPA, while it could reduce the growth of G. apicola in vitro, it did not induce any significant change in the honeybee microbiota, suggesting that glyphosate is the active component modifying the gut communities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.