Evidence map›Paper›PMID 30990758›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Alveolar Macrophage Transcriptional Programs Are Associated with Outcomes in Acute Respiratory Distress Syndrome.

Eric D Morrell, Pavan K Bhatraju, Carmen R Mikacenic, Frank Radella, Anne M Manicone, Renee D Stapleton, Mark M Wurfel, Sina A Gharib

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 78 citations in OpenAlex.

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  14. Circulating Back to Blood: Erythrocyte Precursors Put the Brakes on Acute Lung Injury.American journal of respiratory cell and molecular biology · 2025
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Eric D MorrellDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Pavan K BhatrajuDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Carmen R MikacenicDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Frank RadellaDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Anne M ManiconeDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Renee D StapletonDepartment of Medicine, University of Vermont, Burlington, Vermont.
Mark M WurfelDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.
Sina A GharibDivision of Pulmonary, Critical Care, and Sleep Medicine, Harborview Medical Center, and.ORCID 0000-0002-2480-4367
Harborview Medical Center · USUniversity of Washington · USUniversity of Vermont · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
SCCOR in Translational Research in Acute Lung InjuryP50HL073996 · NHLBI · UNIVERSITY OF WASHINGTON · PI MARTIN, THOMAS R · 2003 to 2007
$15.7M
Integrated Multi-omics of MelioidosisR01AI137111 · NIAID · UNIVERSITY OF WASHINGTON · PI GHARIB, SINA A, WEST, TIMOTHY EOIN · 2018 to 2021
$3.2M
Macrophage Signaling Pathways in Acute Lung Injury and ResolutionR01HL144656 · NHLBI · UNIVERSITY OF WASHINGTON · PI MANICONE, ANNE M. · 2019 to 2022
$2.4M
The Role of Alveolar Mononuclear Phagocytes in Acute Respiratory Distress SyndromeK23HL144916 · NHLBI · UNIVERSITY OF WASHINGTON · PI MORRELL, ERIC DOUGLAS · 2019 to 2023
$951k
The Assessment of Acute Kidney Injury Sub-phenotypes in the Intensive Care UnitK23DK116967 · NIDDK · UNIVERSITY OF WASHINGTON · PI BHATRAJU, PAVAN KUMAR · 2019 to 2023
$938k
Influence of Acute Respiratory Distress Syndrome on Human Alveolar Macrophage PolarityF32HL138746 · NHLBI · UNIVERSITY OF WASHINGTON · PI MORRELL, ERIC DOUGLAS · 2017 to 2017
$70k
NHLBI NIH HHS F32 HL138746NHLBI NIH HHS K23 HL144916NHLBI NIH HHS P50 HL073996NHLBI NIH HHS R01 HL144656NHLBI NIH HHS T32 HL007287NIAID NIH HHS R01 AI137111NIDDK NIH HHS K23 DK116967NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Transcription, GeneticAdultAgedFemaleHumansInflammationMacrophages, AlveolarMaleMiddle AgedRespiration, ArtificialRespiratory Distress SyndromeTime Factorsacute respiratory distress syndromeadultmacrophagetranscriptome

Identifiers

PMID30990758
PMCPMC6775881
OpenAlexW2939248814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.