ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2019
Sex differences in characteristics and outcome in acute coronary syndrome patients in the Netherlands.
Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 47 citations in OpenAlex.
- Occluded Coronary Artery among Non-ST Elevation Myocardial Infarction Patients in Department of Cardiology of a Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2023Trial
- Evaluation of Sex-Based Differences in the Prescription of the Combination of Evidence-Based Medicine After the Occurrence of an Acute ST-Elevation Myocardial Infarction.Clinical cardiology · 2025Article
- Gender-based differences among ST-elevation myocardial infarction patients in Egypt: secondary analysis from the ACCA-EAPCI ESC-STEMI registry.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Sex differences in ST-segment elevation myocardial infarction patients treated by primary percutaneous intervention.Open heart · 2025Article
- Long-term all-cause mortality rate after ST-elevation myocardial infarction and its predictors: ST Elevation Myocardial Infarction Cohort in Isfahan Study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Sex-related differences in acute coronary syndrome: insights from an observational study in a Yemeni cohort.Frontiers in cardiovascular medicine · 2025Article
- Evaluate gender differences in patients with left main coronary artery disease.ARYA atherosclerosis · 2025Article
- Sex differences in outcomes after acute coronary syndrome vary with age: a New Zealand national study.European heart journal. Acute cardiovascular care · 2024Article
- In-hospital mortality of patients with acute coronary syndrome (ACS) after implementation of national health insurance (NHI) in Indonesia.BMC health services research · 2024Article
- Comparison between myocardial infarction with non-obstructive coronaries (MINOCA) and myocardial infarct patients with coronary artery disease (MI-CAD): A single-center retrospective cohort study.Caspian journal of internal medicine · 2024Article
- Sex-Related Differences in Outpatient Healthcare of Acute Coronary Syndrome: Evidence from an Italian Real-World Investigation.Journal of clinical medicine · 2023Article
- Sex Differences in Acute Coronary Syndromes: A Global Perspective.Journal of cardiovascular development and disease · 2022Review
- External validation of the GRACE risk score and the risk-treatment paradox in patients with acute coronary syndrome.Open heart · 2022Article
- Sex related inequalities in the management and prognosis of acute coronary syndrome in Switzerland: cross sectional study.BMJ medicine · 2022Article
- Pharmacological treatment after acute coronary syndrome: Baseline clinical characteristics and gender differences in a population-based cohort study.Atencion primaria · 2022Article
- Trends of Sex Differences in Clinical Outcomes After Myocardial Infarction in the United States.CJC open · 2021Article
- Thyroid Dysfunction in Patients Admitted in Cardiac Care Unit: Prevalence, Characteristic and Hospitalization Outcomes.International journal of general medicine · 2021Article
- Evaluation of sex differences in patients with ST-elevated myocardial infarction: an observational cohort study in Amsterdam and surrounding region.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2020Article
- Sex Differences in the Outcomes of Elderly Patients with Acute Coronary Syndrome.Cardiology research and practice · 2020Article
Corrections and comments
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Authors and funding
13 authors at 11 institutions in 1 country.
Funding
Abstract
backgroundSex differences in acute coronary syndrome (ACS) have been reported, but little is known about the situation in the Netherlands.
methodsThis registry is a merge of available data on ACS patients in the electronic data capture systems of 11 centres with 24/7 interventional cardiology services. We included patients >18 years undergoing a cardiac catheterisation between 2010-2012. We evaluated sex differences in clinical and procedural characteristics and 1‑year mortality.
resultsA total of 29,265 ACS patients (8,720 women and 20,545 men) were registered. Women were on average 4.5 years older (68.5 vs 63.0 years, p < 0.001) and had a higher prevalence of hypertension (62.7 vs 49.8%, p < 0.001) and insulin-dependent diabetes mellitus (9.6 vs 6.8%, p < 0.001) than men. Women less often presented with ST-elevation myocardial infarction (43.7% vs 47.6%, p < 0.001) and appeared to have less extensive coronary artery disease than men. Women less often underwent coronary angiography by radial access (52.5 vs 55.9%, p < 0.001). One-year mortality was higher in women than in men (7.3% and 5.6%, p < 0.001). More specific, the relationship between sex and mortality was age-dependent and showed higher mortality in women ≤71 years, but lower mortality in older women compared with men (p-interaction <0.001).
conclusionWe found differences in clinical and procedural characteristics and outcome between women and men admitted for ACS, which are in line with other Western countries. The limitations of our registry, based on existing local databases, can be overcome by the use of the prospective Netherlands Heart Registry that is currently in development.
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