ArticleEuropean radiology2019
Increased tortuosity of ACA might be associated with increased risk of ACoA aneurysm development and less aneurysm dome size: a computer-aided analysis.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 17 citations in OpenAlex.
- Computer-aided assessment of intracranial arterial tortuosity as a predictor of aneurysm occurrence and instability.Neuroradiology · 2026Article
- Automated segmentation and quantitative analysis of vascular curvature features in unruptured intracranial aneurysms based on time-of-flight magnetic resonance angiography (TOF-MRA).Quantitative imaging in medicine and surgery · 2026Article
- Discrepancy in vessel tortuosity measurements of anterior circulation cerebral artery between digital subtraction angiography and magnetic resonance angiography.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation : A Case-control CFD Study.Clinical neuroradiology · 2024Article
- An Improved Path-Finding Method for the Tracking of Centerlines of Tortuous Internal Carotid Arteries in MR Angiography.Journal of imaging · 2024Article
- Effects of Path-Finding Algorithms on the Labeling of the Centerlines of Circle of Willis Arteries.Tomography (Ann Arbor, Mich.) · 2023Article
- Vascular tortuosity is related to reduced thalamic volume after middle cerebral artery occlusion.Heliyon · 2023Article
- How Cerebral Vessel Tortuosity Affects Development and Recurrence of Aneurysm: Outer Curvature versus Bifurcation Type.Journal of stroke · 2021Article
- Increased tortuosity of basilar artery might be associated with higher risk of aneurysm development.European radiology · 2020Article
- Determination of patient prognosis based on unruptured basilar artery aneurysm morphology using a novel dynamic prediction model.Frontiers in neurologyArticle
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5 authors at 1 institution in 1 country.
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Abstract
objectivesWe decided to perform computer-aided analysis of the anterior cerebral artery (ACA) to check for a potential correlation with anterior communicating artery (ACoA) aneurysm presence and growth.
methodsWe retrospectively analyzed the ACA anatomy of 121 patients with ACoA aneurysms along with 121 age, risk factors, and vessel side-matched control patients without an ACoA aneurysm. We obtained their medical history and digital subtraction angiography (DSA) data from their medical records. For each patient's DSA, we extracted curve representing the course of their ACA and calculated its relative length (RL), sum of angle metrics (SOAM), triangular index (TI), product of angle distance (PAD), and inflection count metrics (ICM).
resultsPatients with ACoA aneurysm had significantly higher RL (0.64 ± 0.23 vs. 0.56 ± 0.22; p < 0.01), SOAM (0.27 ± 0.19 vs. 0.18 ± 0.15; p < 0.01), PAD (0.12 ± 0.13 vs. 0.09 ± 0.11; p = 0.02), and TI (0.57 ± 0.14 vs. 0.44 ± 0.15; p < 0.01). In multivariate logistic regression analysis, after adjustment for possible confounders, SOAM (OR, 1.34; 95% CI, 1.12-1.63; p < 0.01) and TI (OR, 1.84; 95% CI, 1.47-2.35; p < 0.01) remained independently associated with higher risk of ACoA aneurysm. Additionally, we found significant negative correlations between TI and aneurysm dome size (R = - 0.194; p = 0.047).
conclusionsIncreased tortuosity of ACA might increase the risk of ACoA aneurysm development and decrease the risk of aneurysm growth. KEY POINTS: • Anterior cerebral artery's sum of angle metrics is associated with hypertension as well as with history of ischemic stroke and myocardial infarction. • Increased tortuosity of anterior cerebral artery might be associated with anterior communicating artery aneurysm development. • Tortuosity of anterior cerebral artery is negatively correlated with anterior communicating artery aneurysm dome size.
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