Evidence map›Paper›PMID 30988880›Full record

ArticleJournal of dental sciences2019

Oral manifestations of granulomatosis with polyangiitis - Clinical and radiological assessment.

Katarzyna Szczeklik, Anna Włudarczyk, Katarzyna Wawrzycka-Adamczyk, Jacek Górka, Maria Fuks-Kulska, Dagmara Darczuk, Jolanta Pytko-Polończyk, Wojciech Szczeklik

Open access · goldAbstract read
In one paragraph

Article in Journal of dental sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Otolaryngologic manifestations in granulomatosis with Polyangitis: A systematic review of clinical presentations and renal correlation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Oral granulomatosis with polyangiitis a systematic review.Clinical and experimental dental research · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
  6. A Rare Presentation of Wegener's Granulomatosis in ENT.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  7. Oral granulomatosis with polyangiitis.Journal of dental sciences · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Katarzyna SzczeklikDepartment of Integrated Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Krakow, Poland.
Anna Włudarczyk2nd Department of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Katarzyna Wawrzycka-Adamczyk2nd Department of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Jacek Górka2nd Department of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Maria Fuks-KulskaRadiology Department, University Hospital, Krakow, Poland.
Dagmara DarczukDepartment of Periodontology and Clinical Oral Pathology Institute of Dentistry, Jagiellonian University Medical College, Krakow, Poland.
Jolanta Pytko-PolończykDepartment of Integrated Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Krakow, Poland.
Wojciech Szczeklik2nd Department of Medicine, Jagiellonian University Medical College, Krakow, Poland.
Jagiellonian University · PLKrakow Cardiovascular Research Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background/purposeGranulomatosis with polyangiitis (GPA) is a type of primary systemic vasculitis associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). GPA mainly affects medium and small vessels and may manifest in different organs, most commonly upper respiratory tract. Oral lesions occur in 6-13% of GPA patients and might be the first symptom observed by the patient. This study presents the evaluation of orofacial manifestations of patients with GPA. MATERIALS AND

methodsProspective study was conducted between June 2014 and November 2017 in Department of Allergy and Immunology at University Hospital in Krakow. Patients diagnosed with GPA, after medical assessment, were examined including precise dental inspection, bacterial and fungal flora of oral cavity evaluation and Cone Beam Computed Tomography (CBCT) imaging.

resultsNine patients were enrolled in the study. Characteristic for GPA strawberry gingivitis was observed in one patient. Bone destruction and inflammatory lesions in paranasal sinuses was confirmed by CBCT in 55.6% of patients. Fungal infection was revealed in 66.7% of patients.

conclusionThese findings oblige dentists to consult patient with laryngologist or internal medicine physician to establish further diagnostic approach, because early diagnosis of GPA is crucial for implementing appropriate treatment and preventing chronic organ damage.

Indexed as

ANCAGingivitisGranulomatosis with polyangiitisOral mucosaVasculitis

Identifiers

PMID30988880
PMCPMC6445982
OpenAlexW2902346319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.