Safety and Efficacy of Aminolevulinic Acid 10% Topical Gel versus Aminolevulinic Acid 20% Topical Solution Followed by Blue-light Photodynamic Therapy for the Treatment of Actinic Keratosis on the Face and Scalp: A Randomized, Double-blind Study.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

1. Antimicrobial photodynamic therapy in skin wound healing: A systematic review of animal studies.International wound journal · 2020
   Pooled it
2. Painless PDT using 10% aminolevulinate gel and red light: A pilot clinical trial of short-contact protocols to reduce discomfort during illumination.Photodiagnosis and photodynamic therapy · 2025
   Trial
3. Safety and Efficacy of Aminolevulinic Acid Hydrochloride Topical Gel, 10%, with Red Light in the Treatment of Facial Cutaneous Squamous Cell Carcinoma In Situ.The Journal of clinical and aesthetic dermatology · 2026
   Article
4. Expert consensus-based recommendations on the use of photodynamic therapy in actinic keratosis patients.JAAD international · 2025
   Article
5. Red-Light Photodynamic Therapy with 10% Aminolevulinic Acid (ALA) Following Microneedling in the Treatment of Facial Actinic Keratosis: Cosmetic and Clinical Outcomes.The Journal of clinical and aesthetic dermatology · 2025
   Article
6. The Immunogenetic Aspects of Photodynamic Therapy.Advances in experimental medicine and biology · 2022
   Article
7. Photodynamic Therapy with 5-aminolevulinic Acid 10% Gel and Red Light for the Treatment of Actinic Keratosis, Nonmelanoma Skin Cancers, and Acne: Current Evidence and Best Practices.The Journal of clinical and aesthetic dermatology · 2021
   Review
8. Clinical efficacy of tanshinone capsules combined with varying concentrations of 5-ALA-PDT in the treatment of cystic acne.American journal of translational research · 2021
   Article
9. Tolerability of Photodynamic Therapy Using 10% 5-Aminolevulinic Acid Hydrochloride Gel for Treating Actinic Keratoses on Surface Areas Larger than 75cmThe Journal of clinical and aesthetic dermatology · 2020
   Article
10. REGARDING RECENTLY PUBLISHED ARTICLE ON SAFETY AND EFFICACY OF AMINOLEVULINIC ACID 10% TOPICAL GEL VERSUS AMINOLEVULINIC ACID 20% TOPICAL SOLUTION FOLLOWED BY BLUE-LIGHT PHOTODYNAMIC THERAPY FOR TREATMENT OF ACTINIC KERATOSIS.The Journal of clinical and aesthetic dermatology · 2019
    Article
11. Letters to the Editor.The Journal of clinical and aesthetic dermatology · 2019
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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