Evidence map›Paper›PMID 30988758›Full record

ArticleExperimental and therapeutic medicine2019

Ginsenoside Rg1 attenuates high glucose-induced endothelial barrier dysfunction in human umbilical vein endothelial cells by protecting the endothelial glycocalyx.

Tingting Zhu, Honglian Wang, Li Wang, Xia Zhong, Wei Huang, Xian Deng, Hengli Guo, Jianfeng Xiong, Youhua Xu, Junming Fan

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tingting ZhuDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Honglian WangDepartment of Nephrology, The Research Center of Combined Traditional Chinese and Western Medicine, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Li WangDepartment of Nephrology, The Research Center of Combined Traditional Chinese and Western Medicine, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Xia ZhongDepartment of Nephrology, The Research Center of Combined Traditional Chinese and Western Medicine, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Wei HuangDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Xian DengDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Hengli GuoDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Jianfeng XiongDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Youhua XuDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Junming FanDepartment of Traditional Chinese and Western Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Taipa, Macau 999078, P.R. China.
Macau University of Science and Technology · MOSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disruption of the endothelial barrier is essential for vascular complications associated with diabetes mellitus, and damage to the endothelial glycocalyx has been demonstrated to participate in this process. Ginsenoside Rg1 (Rg1), the major active component isolated from

Indexed as

endothelial barrier dysfunctionendothelial glycocalyxginsenoside Rg1heparanase

Identifiers

PMID30988758
PMCPMC6447798
OpenAlexW2921430700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.